Evidence map›Paper›PMID 35326810›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Idiosyncratic Fitness Costs of Ampicillin-Resistant Mutants Derived from a Long-Term Experiment with

Jalin A Jordan, Richard E Lenski, Kyle J Card

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Pairwise Growth Dynamics of EnvironmentalAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jalin A JordanDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Richard E LenskiDepartment of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-1064-8375
Kyle J CardBEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-0462-2777
Cleveland Clinic Lerner College of Medicine · USMichigan State University · USUniversity of Pennsylvania · US

Funding

National Science Foundation DBI-0939454National Science Foundation DEB-1951307United States Department of Agriculture MICL02253
6 · The paper itself

Abstract

Antibiotic resistance is a growing concern that has prompted a renewed focus on drug discovery, stewardship, and evolutionary studies of the patterns and processes that underlie this phenomenon. A resistant strain's competitive fitness relative to its sensitive counterparts in the absence of drug can impact its spread and persistence in both clinical and community settings. In a prior study, we examined the fitness of tetracycline-resistant clones that evolved from five different

Indexed as

antimicrobial resistanceexperimental evolutionfitness costspleiotropyrelative fitnesstradeoffs

Identifiers

PMID35326810
PMCPMC8944548
OpenAlexW4220991864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.