Evidence map›Paper›PMID 35326760›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Antimicrobial Prophylaxis for Urologic Procedures in Paediatric Patients: A RAND/UCLA Appropriateness Method Consensus Study in Italy.

Susanna Esposito, Erika Rigotti, Alberto Argentiero, Caterina Caminiti, Elio Castagnola, Laura Lancella, Elisabetta Venturini, Maia De Luca, Stefania La Grutta, Mario Lima and 7 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Is Preoperative Antimicrobial Prophylaxis Necessary in Testicular Torsion Surgery? Results from the National Surgical Quality Improvement Program Pediatric.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Pediatric Nephrolithiasis.Healthcare (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 1 country.

Susanna EspositoPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Erika RigottiPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy.
Alberto ArgentieroPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Caterina CaminitiResearch and Innovation Unit, University Hospital of Parma, 43126 Parma, Italy.ORCID 0000-0002-3196-2435
Elio CastagnolaInfectious Diseases Unit, IRCCS Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0002-5336-8429
Laura LancellaPaediatric and Infectious Disease Unit, Academic Department of Pediatrics, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Elisabetta VenturiniPediatric Infectious Disease Unit, Meyer Children's Hospital, 50139 Florence, Italy.ORCID 0000-0002-0048-3933
Maia De LucaUnit of Immune and Infectious Diseases, IRCCS Bambino Gesu' Children's Hospital, 00165 Rome, Italy.
Stefania La GruttaInstitute for Biomedical Research and Innovation, National Research Council, 90146 Palermo, Italy.ORCID 0000-0001-8026-0715
Mario LimaPaediatric Surgery, IRCCS Azienda Ospedaliera-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-5877-440X
Simonetta TesoroDivision of Anesthesia, Analgesia, and Intensive Care, Department of Surgical and Biomedical Sciences, University of Perugia, 06129 Perugia, Italy.
Matilde CicciaNeonatal Intensive Care Unit, Department of Women's and Children's Health, Maggiore Hospital, 40133 Bologna, Italy.
Annamaria StaianoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", 80131 Naples, Italy.
Giovanni AutorePediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0002-5895-8313
Giorgio PiacentiniPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy.
Nicola PrincipiUniversità degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-3468-5568
The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group
University of Parma · ITBambino Gesù Children's Hospital · ITUniversity of Verona · ITAzienda USL di Bologna · ITInstitute for Biomedical Research and Innovation · ITIstituto Giannina Gaslini · ITMeyer Children's Hospital · ITOspedale Maggiore · ITUniversity of Milan · ITUniversity of Naples Federico II · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main aim of surgical antimicrobial prophylaxis (SAP) in urologic procedures is to prevent bacteraemia, surgical site infections (SSIs), and postoperative urinary tract infections (ppUTIs). Guidelines for SAP in paediatric urology are lacking. Only some aspects of this complex topic have been studied, and the use of antibiotic prophylaxis prior to surgical procedures seems to be more often linked to institutional schools of thought or experts' opinions than to rules dictated by studies demonstrating the most correct and preferred management. Therefore, the aim of this Consensus document realized using the RAND/UCLA appropriateness method is to provide clinicians with a series of recommendations on SAP for the prevention of bacteraemia, SSIs, and ppUTIs after urologic imaging and surgical procedures in paediatric patients. Despite the few available studies, experts agree on some basilar concepts related to SAP for urologic procedures in paediatric patients. Before any urological procedure is conducted, UTI must be excluded. Clean procedures do not require SAP, with the exception of prosthetic device implantation and groin and perineal incisions where the SSI risk may be increased. In contrast, SAP is needed in clean-contaminated procedures. Studies have also suggested the safety of eliminating SAP in paediatric hernia repair and orchiopexy. To limit the emergence of resistance, every effort to reduce and rationalize antibiotic consumption for SAP must be made. Increased use of antibiotic stewardship can be greatly effective in this regard.

Indexed as

cystoscopyhypospadiaskidney transplantationnephrolithiasisRAND/UCLA methodsurgical antimicrobial prophylaxisurology

Identifiers

PMID35326760
PMCPMC8944721
OpenAlexW4213120867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.