Evidence map›Paper›PMID 35326753›Full record

ReviewAntibiotics (Basel, Switzerland)2022

Effect of Antibiotic Prophylaxis on Surgical Site Infection in Thyroid and Parathyroid Surgery: A Systematic Review and Meta-Analysis.

Andrea Polistena, Francesco Paolo Prete, Stefano Avenia, Giuseppe Cavallaro, Giovanna Di Meo, Alessandro Pasculli, Fabio Rondelli, Alessandro Sanguinetti, Lucia Ilaria Sgaramella, Nicola Avenia and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Andrea PolistenaOncologic and Laparoscopic Surgery, Department of Surgery Pietro Valdoni, Sapienza University of Rome, Policlinico Umberto I, 00161 Roma, Italy.ORCID 0000-0002-1319-1147
Francesco Paolo PreteAcademic Unit of General Surgery, Department of Biomedical Sciences and Human Oncology, School of Medical, University of Bari Aldo Moro, 70120 Bari, Italy.ORCID 0000-0003-0426-8752
Stefano AveniaGeneral and Endocrine Surgery, School of Medical, University of Perugia, S. Maria University Hospital, 05100 Terni, Italy.
Giuseppe CavallaroOncologic and Laparoscopic Surgery, Department of Surgery Pietro Valdoni, Sapienza University of Rome, Policlinico Umberto I, 00161 Roma, Italy.ORCID 0000-0001-7121-2295
Giovanna Di MeoAcademic Unit of General Surgery, Department of Biomedical Sciences and Human Oncology, School of Medical, University of Bari Aldo Moro, 70120 Bari, Italy.
Alessandro PasculliAcademic Unit of General Surgery, Department of Biomedical Sciences and Human Oncology, School of Medical, University of Bari Aldo Moro, 70120 Bari, Italy.
Fabio RondelliGeneral and Endocrine Surgery, School of Medical, University of Perugia, S. Maria University Hospital, 05100 Terni, Italy.
Alessandro SanguinettiGeneral and Endocrine Surgery, School of Medical, University of Perugia, S. Maria University Hospital, 05100 Terni, Italy.
Lucia Ilaria SgaramellaAcademic Unit of General Surgery, Department of Biomedical Sciences and Human Oncology, School of Medical, University of Bari Aldo Moro, 70120 Bari, Italy.
Nicola AveniaGeneral and Endocrine Surgery, School of Medical, University of Perugia, S. Maria University Hospital, 05100 Terni, Italy.
Mario TestiniAcademic Unit of General Surgery, Department of Biomedical Sciences and Human Oncology, School of Medical, University of Bari Aldo Moro, 70120 Bari, Italy.ORCID 0000-0002-9297-4894
Angela GurradoAcademic Unit of General Surgery, Department of Biomedical Sciences and Human Oncology, School of Medical, University of Bari Aldo Moro, 70120 Bari, Italy.
University of Bari Aldo Moro · ITUniversity of Perugia · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid and parathyroid surgery are considered clean procedures, with an incidence of surgical site infection (SSI) after thyroidectomy ranging from 0.09% to 2.9%. International guidelines do not recommend routine antibiotic prophylaxis (AP), while AP seems to be employed commonly in clinical practice. The purpose of this systematic review is analyzing whether the postoperative SSI rate in thyroid and parathyroid surgery is altered by the practice of AP. We searched Pubmed, Scopus, the Cochrane Library, and Web of Science (WOS) for studies comparing AP to no preoperative antibiotics up to October 2021. Data on the SSI rate was evaluated and summarized as relative risks (RR) with 95% confidence intervals (95% CI). Risk of bias of studies were assessed with standard methods. Nine studies (4 RCTs and 5 nRCTs), including 8710 participants, were eligible for quantitative analysis. A meta-analysis showed that the SSI rate was not significantly different between AP and no preoperative antibiotics (SSI rate: 0.6% in AP vs. 2.4% in control group; RR 0.69, 0.43-1.10 95% CI,

Indexed as

antibiotic prophylaxisparathyroidSSIsurgerythyroid

Identifiers

PMID35326753
PMCPMC8944446
OpenAlexW4213188706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.