Evidence map›Paper›PMID 35326644›Full record

ReviewCancers2022

Biomarkers and Genetic Markers of Hepatocellular Carcinoma and Cholangiocarcinoma-What Do We Already Know.

Jacek Baj, Łukasz Bryliński, Filip Woliński, Michał Granat, Katarzyna Kostelecka, Piotr Duda, Jolanta Flieger, Grzegorz Teresiński, Grzegorz Buszewicz, Marzena Furtak-Niczyporuk and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Genetic screening of liver cancer: State of the art.World journal of hepatology · 2024
    Review
  3. Biomarker in Hepatocellular Carcinoma.Indian journal of surgical oncology · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Jacek BajDepartment of Anatomy, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0002-1372-8987
Łukasz BrylińskiDepartment of Forensic Medicine, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0003-4604-6330
Filip WolińskiDepartment of Forensic Medicine, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0002-6444-5645
Michał GranatDepartment of Anatomy, Medical University of Lublin, 20-090 Lublin, Poland.
Katarzyna KosteleckaDepartment of Anatomy, Medical University of Lublin, 20-090 Lublin, Poland.
Piotr DudaDepartment of Anatomy, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0003-0867-6315
Jolanta FliegerDepartment of Analytical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0001-6881-3161
Grzegorz TeresińskiDepartment of Forensic Medicine, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0002-4184-9305
Grzegorz BuszewiczDepartment of Forensic Medicine, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0001-7637-6387
Marzena Furtak-NiczyporukDepartment of Public Health, Medical University of Lublin, 20-093 Lublin, Poland.
Piero PortincasaClinica Medica "A. Murri", Department of Biomedical Sciences & Human Oncology, University of Bari Medical School, 70124 Bari, Italy.ORCID 0000-0001-5359-1471
Medical University of Lublin · PLUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most common primary liver cancer with an increasing worldwide mortality rate. Cholangiocarcinoma (CCA) is the second most common primary liver cancer. In both types of cancers, early detection is very important. Biomarkers are a relevant part of diagnosis, enabling non-invasive detection and control of cancer recurrence, as well as in the application of screening tests in high-risk groups. Furthermore, some of these biomarkers are useful in controlling therapy and treatment selection. Detection of some markers presents higher sensitivity and specificity in combination with other markers when compared with a single detection. Some gene aberrations are also prognostic markers in the two types of cancers. In the following review, we discuss the most common biomarkers and genetic markers currently being used in the diagnosis of hepatocellular carcinoma and cholangiocarcinoma.

Indexed as

biomarkercholangiocarcinomadiagnosisgenetic markerhepatocellular carcinomascreeningtherapytreatment

Identifiers

PMID35326644
PMCPMC8946081
OpenAlexW4220704614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.