Evidence map›Paper›PMID 35326537›Full record

ArticleCancers2022

Downregulation and Hypermethylation of GABPB1 Is Associated with Aggressive Thyroid Cancer Features.

Xiangling Xing, Ninni Mu, Xiaotian Yuan, Na Wang, C Christofer Juhlin, Klas Strååt, Catharina Larsson, Shi Yong Neo, Dawei Xu

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 34 citations in OpenAlex.

  1. NovelInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer.The Journal of clinical endocrinology and metabolism · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Frontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Xiangling XingDepartment of Medicine, Division of Hematology, Bioclinicum J6:20 and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, SE-171 64 Solna, Sweden.
Ninni MuDepartment of Oncology-Pathology, BioClinicum J6:20, Karolinska Institutet, SE-171 64 Solna, Sweden.ORCID 0000-0002-3887-880X
Xiaotian YuanDepartment of Medicine, Division of Hematology, Bioclinicum J6:20 and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, SE-171 64 Solna, Sweden.ORCID 0000-0002-1501-518X
Na WangDepartment of Medicine-Huddinge, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
C Christofer JuhlinDepartment of Oncology-Pathology, BioClinicum J6:20, Karolinska Institutet, SE-171 64 Solna, Sweden.ORCID 0000-0002-5945-9081
Klas StrååtDepartment of Medicine, Division of Hematology, Bioclinicum J6:20 and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, SE-171 64 Solna, Sweden.
Catharina LarssonDepartment of Oncology-Pathology, BioClinicum J6:20, Karolinska Institutet, SE-171 64 Solna, Sweden.
Shi Yong NeoDepartment of Oncology-Pathology, BioClinicum J6:20, Karolinska Institutet, SE-171 64 Solna, Sweden.
Dawei XuDepartment of Medicine, Division of Hematology, Bioclinicum J6:20 and Center for Molecular Medicine, Karolinska University Hospital Solna and Karolinska Institutet, SE-171 64 Solna, Sweden.ORCID 0000-0003-3141-4524
Karolinska University Hospital · SEKarolinska Institutet · SEAgency for Science, Technology and Research · SG

Funding

Lars Hierta Foundation and Karolinska Institutet 2018-01524Swedish Cancer Society No.190018PjSwedish Research Council 2018-02993the Cancer Society in Stockholm 201393
6 · The paper itself

Abstract

Promoter mutations of the telomerase reverse transcriptase (

Indexed as

DNA methylationGABPAGABPB1telomeraseTERTthyroid carcinoma

Identifiers

PMID35326537
PMCPMC8946831
OpenAlexW4220817061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.