Evidence map›Paper›PMID 35326487›Full record

ArticleCells2022

Predation Stress Causes Excessive Aggression in Female Mice with Partial Genetic Inactivation of Tryptophan Hydroxylase-2: Evidence for Altered Myelination-Related Processes.

Evgeniy Svirin, Ekaterina Veniaminova, João Pedro Costa-Nunes, Anna Gorlova, Aleksei Umriukhin, Allan V Kalueff, Andrey Proshin, Daniel C Anthony, Andrey Nedorubov, Anna Chung Kwan Tse and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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  4. Roles of AMPA receptors in social behaviors.Frontiers in synaptic neuroscience · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 7 countries.

Evgeniy SvirinDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0003-3501-574X
Ekaterina VeniaminovaLaboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov University, 119991 Moscow, Russia.
João Pedro Costa-NunesLaboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov University, 119991 Moscow, Russia.ORCID 0000-0003-0127-5420
Anna GorlovaLaboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov University, 119991 Moscow, Russia.
Aleksei UmriukhinLaboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov University, 119991 Moscow, Russia.
Allan V KalueffNeuroscience Program, Sirius University, 354340 Sochi, Russia.ORCID 0000-0002-7525-1950
Andrey ProshinP.K. Anokhin Research Institute of Normal Physiology, 125315 Moscow, Russia.ORCID 0000-0002-7258-7870
Daniel C AnthonyLaboratory of Psychiatric Neurobiology, Institute of Molecular Medicine and Department of Normal Physiology, Sechenov University, 119991 Moscow, Russia.ORCID 0000-0003-1380-6655
Andrey NedorubovInstitute of Translational Medicine and Biotechnology, Sechenov University, 119991 Moscow, Russia.ORCID 0000-0002-5915-7999
Anna Chung Kwan TseLi Ka Shing Faculty of Medicine, School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Susanne WalitzaDepartment for Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, 8032 Zurich, Switzerland.
Lee Wei LimLi Ka Shing Faculty of Medicine, School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.ORCID 0000-0001-6692-6285
Klaus-Peter LeschDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, 6200 MD Maastricht, The Netherlands.
Tatyana StrekalovaDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0001-9937-5600
Sechenov University · RUUniversity of Hong Kong · HKInstitute of Normal Physiology named after P.K. Anokhin · RUUniversity of Lisbon · PTUniversity of Würzburg · DEUniversity of Zurich · CHUral Federal University · RU

Funding

DFG DFG:CRC TRR58A1/A5European Union's Horizon 2020 research and innovation program 101007642, 728018, 602805Priority 2030 Priority 2030- 2022RAS RAS №0520-2019-0031Swiss-Russian Cooperation grant RPG Russia 2020 RPG Russia 2020the University of Hong Kong Seed Fund for Basic Research 201604159006, 201611159234
6 · The paper itself

Abstract

The interaction between brain serotonin (5-HT) deficiency and environmental adversity may predispose females to excessive aggression. Specifically, complete inactivation of the gene encoding tryptophan hydroxylase-2 (

Indexed as

SerotoninAggressionAnimalsFemaleGlycogen Synthase Kinase 3 betaMaleMicePredatory BehaviorRatsTryptophan HydroxylaseGlycogen Synthase Kinase 3 betaSerotoninTph2 protein, mouseTryptophan Hydroxylase5-HT receptorsfemale aggressionglycogen synthase kinase-3 β (GSK-3β)myelinationpredation stresstryptophan hydroxylase-2 (Tph2)

Identifiers

PMID35326487
PMCPMC8947002
OpenAlexW4221069841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.