Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
19 authors at 5 institutions in 4 countries.
Antoine MarchandUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.ORCID 0000-0002-3511-0088
Alessia SarchioneUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.
Panagiotis S AthanasopoulosDepartment of Cell Biochemistry, University of Groningen, 9747 AG Groningen, The Netherlands.ORCID 0000-0002-2255-9433
Hélène Bauderlique-Le RoyBioImaging Center Lille, UMS 2014-US 41-PLBS, F-59000 Lille, France.
Liesel GoveasUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.ORCID 0000-0003-0925-5870
Romain MagnezUniversity of Lille, CNRS, Inserm, CHU Lille, UMR9020-UMR1277-Canther-Cancer Heterogeneity Plasticity and Resistance to Therapies, Platform of Integrative Chemical Biology, F-59000 Lille, France.ORCID 0000-0002-1882-8469
Matthieu DrouyerUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.
Marco EmanueleUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.
Franz Y HoDepartment of Cell Biochemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Maxime LiberelleUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.
Patricia MelnykUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.ORCID 0000-0002-9555-3446
Nicolas LebègueUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.ORCID 0000-0003-4245-2833
Xavier ThuruUniversity of Lille, CNRS, Inserm, CHU Lille, UMR9020-UMR1277-Canther-Cancer Heterogeneity Plasticity and Resistance to Therapies, Platform of Integrative Chemical Biology, F-59000 Lille, France.ORCID 0000-0002-0998-4160
R Jeremy NicholsDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Elisa GreggioPhysiology, Genetics and Behavior Unit, Department of Biology, University of Padova, 35131 Padova, Italy.
Arjan KortholtDepartment of Cell Biochemistry, University of Groningen, 9747 AG Groningen, The Netherlands.ORCID 0000-0001-8174-6397
Thierry GalliInstitute of Psychiatry and Neuroscience of Paris, Université Paris Cité, INSERM U1266, F-75014 Paris, France.ORCID 0000-0001-8514-7455
Marie-Christine Chartier-HarlinUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.ORCID 0000-0001-6416-6526
Jean-Marc TaymansUniversity of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.ORCID 0000-0001-5503-5524
Inserm · FRUniversity of Groningen · NLCentre National de la Recherche Scientifique · FRStanford University · USUniversity of Padua · IT
Funding
Agence Nationale de la Recherche ANR-16-CE16-0012-02Agence Nationale de la Recherche ANR-20-CE16-0008Agence Nationale de la Recherche ANR-21-CE16 PARK-PEPFondation de France R19199EKFrance Parkinson R16008Michael J. Fox Foundation 10255.03Michael J. Fox Foundation 12938.04Michael J. Fox Foundation 6709.03
6 · The paper itself
Abstract
The
Indexed as
Parkinson DiseaseHumansLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LysosomesPhosphorylationSignal TransductionLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LRRK2 protein, humanLRRK2lysosomeParkinson’s diseasephosphorylationRABs
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively. · full record | OpenQuestion