Evidence map›Paper›PMID 35326462›Full record

ArticleCells2022

Vogt-Koyanagi-Harada Disease Exacerbation Associated with COVID-19 Vaccine.

Begoña De Domingo, Miguel López, Maria Lopez-Valladares, Esperanza Ortegon-Aguilar, Bernardo Sopeña-Perez-Argüelles, Francisco Gonzalez

Open access · goldAbstract readCase Reports
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Vogt-Koyanagi-Harada Disease and COVID.Journal of clinical medicine · 2023
    Review
  5. Ocular manifestations following COVID-19 vaccination.Journal of ophthalmic inflammation and infection · 2023
    Article
  6. Challenges in posterior uveitis-tips and tricks for the retina specialist.Journal of ophthalmic inflammation and infection · 2023
    Review
  7. Article
  8. Correction.Human vaccines & immunotherapeutics · 2023
    Article
  9. A COVID-19 perspective of Vogt-Koyanagi-Harada disease.Indian journal of ophthalmology · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Begoña De DomingoService of Ophthalmology, Instituto de Investigación Sanitaria (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Miguel LópezNeurObesity Group, Department of Physiology, CIMUS, Instituto de Investigación Sanitaria, University of Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-7823-1648
Maria Lopez-ValladaresService of Ophthalmology, Instituto de Investigación Sanitaria (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Esperanza Ortegon-AguilarService of Neurology, Complejo Hospitalario Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Bernardo Sopeña-Perez-ArgüellesService of Internal Medicine, Complejo Hospitalario Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Francisco GonzalezService of Ophthalmology, Instituto de Investigación Sanitaria (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Complejo Hospitalario Universitario de Santiago · ESUniversidade de Santiago de Compostela · ES

Funding

European Union EURONANOMED2019-050-ENAMEPInstituto de Salud Carlos III RETICS RD16/0008/0003Ministry of Economy, Industry and Competitiveness RTI2018-101840-B-I00Xunta de Galicia ED431G 2019/02
6 · The paper itself

Abstract

We describe a case of Vogt-Koyanagi-Harada (VKH) disease exacerbation after COVID-19 vaccination. A 46-year-old woman presented with a bilateral granulomatous uveitis 2 days after the first dose of COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech), and was diagnosed with a complete Vogt-Koyanagi-Harada (VKH) disease 4 days after receiving the second dose of the vaccine. Three weeks before the first dose, she had been consulted for blurred vision and mild headaches. The case resolved with high dose intravenous corticosteroids, followed by oral prednisone. The close temporal relationship between the COVID-19 vaccine doses and the worsening of VKH symptoms strongly suggests COVID-19 vaccination as the trigger of its exacerbation.

Indexed as

COVID-19UveitisUveomeningoencephalitic SyndromeCOVID-19 VaccinesFemaleHumansMiddle AgedmRNA VaccinesVaccines, SyntheticCOVID-19 VaccinesmRNA VaccinesVaccines, SyntheticCOVID-19 vaccineuveitisvaccine-associated autoimmunityvitiligoVKH disease

Identifiers

PMID35326462
PMCPMC8947156
OpenAlexW4221095893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.