Evidence map›Paper›PMID 35326451›Full record

ReviewCells2022

Bioenergetic Aspects of Mitochondrial Actions of Thyroid Hormones.

Federica Cioffi, Antonia Giacco, Fernando Goglia, Elena Silvestri

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Endocrine-Metabolic Crosstalk Between Diabetes Mellitus and Hypothyroidism: From Network Mechanisms to Translational Stratification.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Federica CioffiDepartment of Science and Technology, University of Sannio, Via De Sanctis, 82100 Benevento, Italy.
Antonia GiaccoDepartment of Science and Technology, University of Sannio, Via De Sanctis, 82100 Benevento, Italy.
Fernando GogliaDepartment of Science and Technology, University of Sannio, Via De Sanctis, 82100 Benevento, Italy.
Elena SilvestriDepartment of Science and Technology, University of Sannio, Via De Sanctis, 82100 Benevento, Italy.
University of Sannio · IT

Funding

"Progetto di Ricerca di rilevante Interesse Nazionale (PRIN)" 2017 2017J92TM5_003
6 · The paper itself

Abstract

Much is known, but there is also much more to discover, about the actions that thyroid hormones (TH) exert on metabolism. Indeed, despite the fact that thyroid hormones are recognized as one of the most important regulators of metabolic rate, much remains to be clarified on which mechanisms control/regulate these actions. Given their actions on energy metabolism and that mitochondria are the main cellular site where metabolic transformations take place, these organelles have been the subject of extensive investigations. In relatively recent times, new knowledge concerning both thyroid hormones (such as the mechanisms of action, the existence of metabolically active TH derivatives) and the mechanisms of energy transduction such as (among others) dynamics, respiratory chain organization in supercomplexes and cristes organization, have opened new pathways of investigation in the field of the control of energy metabolism and of the mechanisms of action of TH at cellular level. In this review, we highlight the knowledge and approaches about the complex relationship between TH, including some of their derivatives, and the mitochondrial respiratory chain.

Indexed as

MitochondriaThyroid HormonesEnergy MetabolismMitochondrial MembranesThyroid Hormonesbioenergeticsiodothyroninesmitochondrial proteomics

Identifiers

PMID35326451
PMCPMC8947633
OpenAlexW4220999549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.