Evidence map›Paper›PMID 35326446›Full record

ArticleCells2022

A Novel 3D Culture System Using a Chitin-Based Polysaccharide Material Produces High-Quality Allogeneic Human UCMSCs with Dispersed Sphere Morphology.

Katsuhiko Kida, Tatsuro Kanaki, Shuang Gao, Daisuke Hatanaka, Masashi Iwakami, Shuai Liu, Masato Horikawa, Minoru Ono, Dehua Chang

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Cell-Based Therapies for Degenerative Musculoskeletal Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Katsuhiko KidaBiological Research Laboratories, Nissan Chemical Corporation, Shiraoka 349-0294, Saitama, Japan.ORCID 0000-0003-2956-0784
Tatsuro KanakiBiological Research Laboratories, Nissan Chemical Corporation, Shiraoka 349-0294, Saitama, Japan.
Shuang GaoBOE Regenerative Medicine Technology Co., Ltd., C2 Building, No.9 Jiuxianqiaobei Road, Chaoyang, Beijing 100015, China.ORCID 0000-0001-5785-7820
Daisuke HatanakaMaterials Research Laboratories, Nissan Chemical Corporation, Funabashi 274-0052, Chiba, Japan.
Masashi IwakamiBiological Research Laboratories, Nissan Chemical Corporation, Shiraoka 349-0294, Saitama, Japan.
Shuai LiuBOE Regenerative Medicine Technology Co., Ltd., C2 Building, No.9 Jiuxianqiaobei Road, Chaoyang, Beijing 100015, China.
Masato HorikawaBiological Research Laboratories, Nissan Chemical Corporation, Shiraoka 349-0294, Saitama, Japan.
Minoru OnoDepartment of Cardiac Surgery, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku 113-8655, Tokyo, Japan.ORCID 0000-0001-6443-8042
Dehua ChangDepartment of Cell Therapy in Regenerative Medicine, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku 113-8655, Tokyo, Japan.
Nissan Chemical Corporation (Japan) · JPBOE Technology Group (China) · CNUniversity of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cell (MSC) transplantation, in particular allogeneic transplantation, is a promising therapy for a variety of diseases. However, before performing allograft treatment it is necessary to find suitable donors, establish culture methods that maintain cell quality, and reduce cell production costs. Here, we present a new method of producing allogeneic MSCs combining human umbilical cord-derived mesenchymal stem cells (UCMSCs) and chitin-based polysaccharide fibers (Cellhesion

Indexed as

Hematopoietic Stem Cell TransplantationMesenchymal Stem CellsMesenchymal Stem Cell TransplantationChitinHumansUmbilical CordChitin3D cultureallogeneic transplantationhuman umbilical cord mesenchymal stem cellsparacrine factorsstemness

Identifiers

PMID35326446
PMCPMC8947357
OpenAlexW4220965806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.