Evidence map›Paper›PMID 35326440›Full record

ArticleCells2022

Cooling Uncouples Differentially ROS Production from Respiration and Ca

Neven Stevic, Jennifer Maalouf, Laurent Argaud, Noëlle Gallo-Bona, Mégane Lo Grasso, Yves Gouriou, Ludovic Gomez, Claire Crola Da Silva, René Ferrera, Michel Ovize and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Neven StevicUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Jennifer MaaloufUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Laurent ArgaudUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Noëlle Gallo-BonaUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Mégane Lo GrassoUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Yves GouriouUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.ORCID 0000-0003-2565-4935
Ludovic GomezUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Claire Crola Da SilvaUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
René FerreraUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Michel OvizeUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Martin CourUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.ORCID 0000-0003-4909-9761
Gabriel BidauxUniv-Lyon, CarMeN Laboratory, Inserm U1060, Université Claude Bernard Lyon 1, INSA Lyon, F-69550 Bron, France.
Université Claude Bernard Lyon 1 · FR

Funding

Agence Nationale de la Recherche ANR-10-IBHU-004Agence Nationale de la Recherche ANR-16-RHUS-0009Fondation Leducq 16 CVD 04
6 · The paper itself

Abstract

Hypothermia provides an effective neuro and cardio-protection in clinical settings implying ischemia/reperfusion injury (I/R). At the onset of reperfusion, succinate-induced reactive oxygen species (ROS) production, impaired oxidative phosphorylation (OXPHOS), and decreased Ca

Indexed as

BrainMitochondria, HeartAnimalsHomeostasisMiceReactive Oxygen SpeciesRespirationReactive Oxygen Speciesbrain mitochondriaCa2+ retention capacitycoldheart mitochondriaischemia/reperfusionMCUmitochondrial functionsmitochondrial respirationreactive oxygen speciesreverse electron transport

Identifiers

PMID35326440
PMCPMC8947173
OpenAlexW4220904275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.