Evidence map›Paper›PMID 35326286›Full record

ArticleBrain sciences2022

Management of Cavernous Carotid Artery Aneurysms: A Retrospective Single-Center Experience.

Michael Karl Fehrenbach, Eric Dietel, Tim Wende, Johannes Kasper, Caroline Sander, Florian Wilhelmy, Ulf Quaeschling, Juergen Meixensberger, Ulf Nestler

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Natural history and treatment of asymptomatic unruptured carotid cavernous aneurysms: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael Karl FehrenbachDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0001-8396-7740
Eric DietelDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0001-7518-8691
Tim WendeDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0002-8634-8897
Johannes KasperDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0003-2122-2676
Caroline SanderDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Florian WilhelmyDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Ulf QuaeschlingInstitute of Neuroradiology, University Hospital Leipzig, 04103 Leipzig, Germany.
Juergen MeixensbergerDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Ulf NestlerDepartment of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0002-2963-4344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWhile cavernous carotid aneurysms can cause neurological symptoms, their often-uneventful natural course and the increasing options of intravascular aneurysm closure call for educated decision-making. However, evidence-based guidelines are missing. Here, we report 64 patients with cavernous carotid aneurysms, their respective therapeutic strategies, and follow-up.

methodsWe included all patients with cavernous carotid aneurysms who presented to our clinic between 2014 and 2020 and recorded comorbidities (elevated blood pressure, diabetes mellitus, and nicotine consumption), PHASES score, aneurysm site, size and shape, therapeutic strategy, neurological deficits, and clinical follow-up.

resultsThe mean age of the 64 patients (86% female) was 53 years, the mean follow-up time was 3.8 years. A total of 22 patients suffered from cranial nerve deficit. Of these patients, 50% showed a relief of symptoms regardless of the therapy regime. We found no significant correlations between aneurysm size or PHASES score and the occurrence of neurological symptoms.

conclusionIf aneurysm specific symptoms persist over a longer period of time, relief is difficult to achieve despite aneurysm treatment. Patients should be advised by experts in neurovascular centers, weighing the possibility of an uneventful course against the risks of treatment. In this regard, more detailed prospective data is needed to improve individual patient counseling.

Indexed as

cavernous carotid aneurysmcranial nerve deficitsflow diversion

Identifiers

PMID35326286
PMCPMC8946508

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.