Evidence map›Paper›PMID 35326281›Full record

ArticleBrain sciences2022

Naturalistic Study of Depression Associated with Parkinson's Disease in a National Public Neurological Referral Center in Mexico.

Reinhard Janssen-Aguilar, Patricia Rojas, Elizabeth Ruiz-Sánchez, Mayela Rodriguez-Violante, Yessica M Alcántara-Flores, Daniel Crail-Meléndez, Amin Cervantes-Arriaga, Óscar Sánchez-Escandón, Ángel A Ruiz-Chow

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Reinhard Janssen-AguilarDepartment of Psychiatry, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.
Patricia RojasLaboratory of Neurotoxicology, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.ORCID 0000-0001-9079-3267
Elizabeth Ruiz-SánchezLaboratory of Neurotoxicology, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.ORCID 0000-0002-8184-0532
Mayela Rodriguez-ViolanteMovement Disorders Clinic, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.
Yessica M Alcántara-FloresLaboratory of Neurotoxicology, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.
Daniel Crail-MeléndezDepartment of Psychiatry, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.ORCID 0000-0002-7272-8119
Amin Cervantes-ArriagaMovement Disorders Clinic, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.
Óscar Sánchez-EscandónClinic of Sleep Disorders, Metropolitan Autonomous University, Mexico City 14387, Mexico.
Ángel A Ruiz-ChowDepartment of Psychiatry, National Institute of Neurology and Neurosurgery Manuel Velasco Suárez, Av. Insurgentes Sur No. 3877, Mexico City 14269, Mexico.
Instituto Nacional de Neurología y Neurocirugía · MXCentro Médico ABC · MXUniversidad Autónoma Metropolitana · MX

Funding

National Council of Science and Technology of Mexico (CONACyT) SALUD-2011-1-162087
6 · The paper itself

Abstract

Major depressive disorder (MDD) is a major health problem in Parkinson's disease (PD) patients. We described the clinical and sociodemographic factors of MDD among patients with PD at a national neurological referral center in Mexico. One hundred patients with PD + MDD were included in the study. All the patients were evaluated during the "ON" treatment phase of PD. Clinical scales for cognition (MMSE and MoCA) and MDD (MADRS) were applied. The mean age was 58.49 ± 11.02 years, and 57% of the sample was male. The most frequent symptom of PD was tremor (67%), and onset was more frequent on the right side (57%). Additionally, 49% of the patients with PD had moderate to severe (M/S) MDD. Selective serotonin reuptake inhibitors were the most frequent antidepressant treatment (69%). The scores of the scales were MADRS 21.33 ± 5.49, MoCA 21.06 ± 4.65, and MMSE 26.67 ± 1.20. The females had lower MMSE scores compared to the males (

Indexed as

major depressive disorderneurodegenerative diseasenon-motor symptomsParkinson’s disease

Identifiers

PMID35326281
PMCPMC8945969
OpenAlexW4214757259

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.