Evidence map›Paper›PMID 35326264›Full record

ArticleBrain sciences2022

Depicting People in Visual Cues Affects Alcohol Cue Reactivity in Male Alcohol-Dependent Patients.

Abdulqawi Alarefi, Xunshi Wang, Rui Tao, Qinqin Rui, Guoqing Gao, Ying Wang, Liangjun Pang, Chialun Liu, Xiaochu Zhang

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdulqawi AlarefiDepartment of Radiology, The First Affiliated Hospital of USTC, School of Life Science, Division of Life Science and Medicine, University of Science & Technology of China, Hefei 230027, China.ORCID 0000-0002-7821-5461
Xunshi WangAffiliated Psychological Hospital of Anhui Medical University, Hefei Fourth People's Hospital, Anhui Mental Health Center, Hefei 230017, China.ORCID 0000-0002-2380-4189
Rui TaoAffiliated Psychological Hospital of Anhui Medical University, Hefei Fourth People's Hospital, Anhui Mental Health Center, Hefei 230017, China.
Qinqin RuiAffiliated Psychological Hospital of Anhui Medical University, Hefei Fourth People's Hospital, Anhui Mental Health Center, Hefei 230017, China.
Guoqing GaoAffiliated Psychological Hospital of Anhui Medical University, Hefei Fourth People's Hospital, Anhui Mental Health Center, Hefei 230017, China.
Ying WangDepartment of Radiology, The First Affiliated Hospital of USTC, School of Life Science, Division of Life Science and Medicine, University of Science & Technology of China, Hefei 230027, China.
Liangjun PangAffiliated Psychological Hospital of Anhui Medical University, Hefei Fourth People's Hospital, Anhui Mental Health Center, Hefei 230017, China.
Chialun LiuDepartment of Radiology, The First Affiliated Hospital of USTC, School of Life Science, Division of Life Science and Medicine, University of Science & Technology of China, Hefei 230027, China.
Xiaochu ZhangDepartment of Radiology, The First Affiliated Hospital of USTC, School of Life Science, Division of Life Science and Medicine, University of Science & Technology of China, Hefei 230027, China.ORCID 0000-0002-7541-0130

Funding

Anhui Medical University 2019xkj098Anhui Mental Health Center 2019LH05Major Project of Philosophy and Social Science Research, Ministry of Education of China 19JZD010The Chinese Academy of Sciences Taiwan Young Talent Programme 2018TW2BB0001The National Key Basic Research Program 2016YFA0400900 and 2018YFC0831101The National Natural Science Foundation of China 31900766, 71942003, 31771221, 61773360, and 71874170
6 · The paper itself

Abstract

Cue reactivity is often used to study alcohol cues brain responses. Standardized image sets are used, but the effect of viewing people interacting with the alcohol drink remains unclear, which is associated with the factors of alcohol cues that influence the degree of response to alcohol stimuli. The present study used fMRI to investigate the reactivity of alcohol dependence (AD) inpatients to alcohol cues with or without human drinking behavior. Cues with a human interacting with a drink were hypothesized to increase sensorimotor activation. In total, 30 AD inpatients were asked to view pictures with a factorial design of beverage types (alcoholic vs. non-alcoholic beverages) and cue types (with or without drink action). Whole-brain analyses were performed. A correlation analysis was conducted to confirm whether the whole-brain analysis revealed cue-related brain activations correlated with problem drinking duration. The left lingual gyrus showed significant beverage types through cue type interaction, and the bilateral temporal cortex showed significant activation in response to alcohol cues depicting human drinking behavior. The right and left lingual gyrus regions and left temporal cortex were positively correlated with problem drinking duration. Sensorimotor activations in the temporal cortex may reflect self-referential and memory-based scene processing. Thus, our findings indicate these regions are associated with alcohol use and suggest them for cue exposure treatment of alcohol addiction.

Indexed as

alcoholcravingcue reactivityfMRIsensorimotor

Identifiers

PMID35326264
PMCPMC8946691

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.