Evidence map›Paper›PMID 35326223›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Evaluation of Label-Free Confocal Raman Microspectroscopy for Monitoring Oxidative Stress In Vitro in Live Human Cancer Cells.

Jakub Maciej Surmacki, Isabel Quiros-Gonzalez, Sarah Elizabeth Bohndiek

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Oxidative Stress and Age-Related Tumors.Antioxidants (Basel, Switzerland) · 2024
    Review
  3. Monitoring alterations of all-RSC advances · 2024
    Article
  4. Article
  5. The immunomodulatory effects of metformin in LPS-induced macrophages: an in vitro study.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  6. Article
  7. Analytical Techniques for Single-Cell Biochemical Assays of Lipids.Annual review of biomedical engineering · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Jakub Maciej SurmackiDepartment of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK.ORCID 0000-0001-6654-0286
Isabel Quiros-GonzalezDepartment of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK.
Sarah Elizabeth BohndiekDepartment of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK.ORCID 0000-0003-0371-8635
Lodz University of Technology · PLUniversidad de Oviedo · ESUniversity of Cambridge · GB

Funding

Cancer Research UK 16267Cancer Research UK C14303/A17197, C47594/A16267Wellcome Trust
6 · The paper itself

Abstract

Understanding the impact of free radicals and antioxidants in cell biology is vital; however, noninvasive nonperturbative imaging of oxidative stress remains a challenge. Here, we evaluated the ability of label-free Raman spectroscopy to monitor redox biochemical changes in antioxidant (

Indexed as

fluorescence microscopyN-acetyl-l-cysteineoxidative stressRaman microspectroscopytert-butyl hydroperoxide

Identifiers

PMID35326223
PMCPMC8945565
OpenAlexW4220869364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.