Evidence map›Paper›PMID 35326220›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Assessment of Melatonin-Cultured Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials for Wound Healing.

Beata Kaczmarek-Szczepańska, Judith M Pin, Lidia Zasada, Mauritz M Sonne, Russel J Reiter, Andrzej T Slominski, Kerstin Steinbrink, Konrad Kleszczyński

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Biopolymeric Scaffolds with Melatonin for Tissue Engineering-A Review.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Hyaluronic Acid/Ellagic Acid as Materials for Potential Medical Application.International journal of molecular sciences · 2024
    Article
  7. Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beata Kaczmarek-SzczepańskaDepartment of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Toruń, Poland.ORCID 0000-0002-2563-2376
Judith M PinDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0001-9146-609X
Lidia ZasadaDepartment of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Toruń, Poland.
Mauritz M SonneDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0003-3991-2376
Russel J ReiterUT Health Science Center, Department of Cellular and Structural Biology, San Antonio, TX 78229, USA.ORCID 0000-0001-6763-4225
Andrzej T SlominskiDepartment of Dermatology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-8963-3995
Kerstin SteinbrinkDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0002-0500-2158
Konrad KleszczyńskiDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0002-1311-263X

Funding

Deutsche Forschungsgemeinschaft KL2900/2-1 (K.K.), TR156/C05-246807620 (K.S.), SFB1009/B11-194468054 (K.S.), SFB1066/B06-213555243 (K.S.), SFB1450/C06-431460824 (K.S.)Nicoluas Copernicus University in Torun 282/2021 IDUB SD (B.K.S.)NIH HHS 1R01AR073004, R01AR071189, R21AI149267-01A1, VA merit 1I01BX004293-01A1 to ATS
6 · The paper itself

Abstract

Chitosan (CTS) and collagen (Coll) are natural biomaterials that have been extensively used in tissue engineering or wound healing applications, either separately or as composite materials. Most methods to fabricate CTS/Coll matrices employ chemical crosslinking to obtain solid and stable scaffolds with the necessary porosity and mechanical properties to facilitate regeneration. In this study, we comparatively assessed the physicochemical properties of 3D scaffolds loaded with a cross-linker, glyoxal. Using a scanning electron microscope, we evaluated the microstructure of resultant matrices and their mechanistic testing by the determination of the compressive modulus (E

Indexed as

biopolymerschitosancutaneous cellsglyoxalmelatoninscaffoldswound healing

Identifiers

PMID35326220
PMCPMC8945360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.