Evidence map›Paper›PMID 35326172›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Enzymatic Epoxidation of Long-Chain Terminal Alkenes by Fungal Peroxygenases.

Esteban D Babot, Carmen Aranda, Jan Kiebist, Katrin Scheibner, René Ullrich, Martin Hofrichter, Angel T Martínez, Ana Gutiérrez

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Vesicle-based cell-free synthesis of short and long unspecific peroxygenases.Frontiers in bioengineering and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Esteban D BabotInstituto de Recursos Naturales y Agrobiología de Sevilla, Consejo Superior de Investigaciones Científicas (CSIC), 41012 Seville, Spain.ORCID 0000-0001-5539-1721
Carmen ArandaJohnson Matthey, Cambridge Science Park U260, Cambridge CB4 0FP, UK.
Jan KiebistInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, 01968 Senftenberg, Germany.
Katrin ScheibnerInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, 01968 Senftenberg, Germany.
René UllrichUnit of Bio- and Environmental Sciences, International Institute Zittau, TU Dresden, 02763 Zittau, Germany.
Martin HofrichterUnit of Bio- and Environmental Sciences, International Institute Zittau, TU Dresden, 02763 Zittau, Germany.ORCID 0000-0001-5174-7604
Angel T MartínezCentro de Investigaciones Biológicas "Margarita Salas", Consejo Superior de Investigaciones Científicas (CSIC), 28040 Madrid, Spain.ORCID 0000-0002-1584-2863
Ana GutiérrezInstituto de Recursos Naturales y Agrobiología de Sevilla, Consejo Superior de Investigaciones Científicas (CSIC), 41012 Seville, Spain.
Consejo Superior de Investigaciones Científicas · ESBrandenburg University of Technology Cottbus-Senftenberg · DEInternational University Institute · DEJohnson Matthey (United Kingdom) · GB

Funding

BioBased Industries Joint Undertaking -EU 792063
6 · The paper itself

Abstract

Terminal alkenes are among the most attractive starting materials for the synthesis of epoxides, which are essential and versatile intermediate building blocks for the pharmaceutical, flavoring, and polymer industries. Previous research on alkene epoxidation has focused on the use of several oxidizing agents and/or different enzymes, including cytochrome P450 monooxygenases, as well as microbial whole-cell catalysts that have several drawbacks. Alternatively, we explored the ability of unspecific peroxygenases (UPOs) to selectively epoxidize terminal alkenes. UPOs are attractive biocatalysts because they are robust extracellular enzymes and only require H

Indexed as

epoxidationepoxidesoxyfunctionalizationperoxygenasesterminal alkenes

Identifiers

PMID35326172
PMCPMC8944640
OpenAlexW4220896298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.