Evidence map›Paper›PMID 35326026›Full record

ArticleIndian journal of ophthalmology2022

Ologen implant versus mitomycin C in combined trabeculectomy and phacoemulsification.

Chandrima Paul, J Divya, Richa Kamal, Anujeet Paul

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Chandrima PaulGlaucoma Services, Director; B B Eye Foundation, Kolkata, West Bengal, India.
J DivyaComprehensive Ophthalmology; B B Eye Foundation, Kolkata, West Bengal, India.
Richa KamalVitreo-Retinal Surgery; B B Eye Foundation, Kolkata, West Bengal, India.
Anujeet PaulDepartment of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.
Creative Commons · USMahatma Gandhi Medical College and Research Institute · INTennessee Retina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To comparatively evaluate in Indian eyes with coexisting cataract and primary open-angle glaucoma the outcome of mitomycin C (MMC) and Ologen implant as adjunctives in combined phacoemulsification with trabeculectomy. Methods: Eyes with primary open-angle glaucoma that underwent trabeculectomy and phacoemulsification with IOL implantation with either MMC application or Ologen implant between June 2019 and February 2020 were followed up for 12 months. Thirty-four eyes of 34 participants were studied. The primary outcome was intraocular pressure (IOP), and the secondary outcomes were the number of ocular hypotensives, best distance visual acuity (BDVA), and bleb morphology. Results: In 16 eyes treated with MMC and 18 eyes treated with Ologen implant, it was observed that the mean postoperative IOP (14.62 ± 2.89 mm Hg with MMC and 14.56 ± 4.14 mm Hg with Ologen implant) was not significantly different in both groups (P = 0.47). Number of ocular hypotensives and BDVA were also comparable between the two groups. However, bleb morphology was better with Ologen implantation. One eye in the MMC group developed hypotony which was conservatively managed. Conclusion: MMC and Ologen are both effective adjunctives in combined phaco-trabeculectomy. However, the Ologen implant provides better bleb health and safety.

Indexed as

Glaucoma, Open-AnglePhacoemulsificationTrabeculectomyAlkylating AgentsCollagenFollow-Up StudiesGlycosaminoglycansHumansIntraocular PressureMitomycinTreatment OutcomeAlkylating AgentsCollagencollagen-glycosaminoglycan copolymerGlycosaminoglycansMitomycinBleb morphologybleb safetyMitomycin COlogenphaco-trabeculectomy

Identifiers

PMID35326026
PMCPMC9240563
OpenAlexW4220963917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.