Evidence map›Paper›PMID 35326023›Full record

ArticleIndian journal of ophthalmology2022

Comparison of uveal parameters between acute primary angle-closure eyes and fellow eyes in South Indian population.

Vijayalakshmi A Senthilkumar, Chinmayee Pradhan, Sharmila Rajendrababu, R Krishnadas, Iswarya Mani

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vijayalakshmi A SenthilkumarDepartment of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India.
Chinmayee PradhanDepartment of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India.
Sharmila RajendrababuDepartment of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India.
R KrishnadasDepartment of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India.
Iswarya ManiDepartment of Biostatistics, Aravind Eye Hospital and Postgraduate Institute of Ohthalmology, Tamil Nadu, India.
Aravind Eye Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: : To analyze the ocular biometric parameters of eyes with acute primary angle closure (APAC) as compared to fellow eyes. Methods: : A cross-sectional study was conducted on 27 patients presenting with recent onset APAC to a tertiary eye institute in India. Anterior and posterior ocular biometric parameters were measured simultaneously by anterior segment optical coherence tomography (AS-OCT), A-scan, ultrasound biomicroscopy (UBM), and B-mode ultrasonogram (USG). The parameters measured were anterior chamber depth (ACD), anterior chamber angle (ACA), angle opening distance (AOD500, AOD750), lens vault (LV), axial length (AL), ciliary body thickness maximum (CBTmax) and at the point of scleral spur (CBT0), anterior placement of the ciliary body (APCB), and retinochoroidal thickness (RCS). Results: Mean age ± SD of patients with APAC was 55.66 ± 7.2 years with female preponderance (21:6 patients). Mean presenting IOP ± SD of the affected eye and fellow eye were 54.74 ± 11.67 mm Hg and 18.7 ± 11.67 mm Hg, respectively. Eyes with APAC had statistically significant narrower anterior ocular biometric parameters, higher LV, decreased ciliary body thickness, more APCB, and longer AL than the fellow eyes. CBTmax is the only variable that had significance (β = -0.421,95% CI: -0.806 to - 0.035, P = 0.034) in the univariate analysis with RCS thickness in APAC eyes. Further, there was a correlation between CBT0 and APCB with CBTmax both in univariate (β = 0.894, P < 0.0001 and β = -0.351, P = 0.039) and multivariable analysis (β = 0.911, P < 0.0001 and β = -0.416, P = 0.016). Conclusion: Compared to the fellow eyes, APAC eyes had different ocular biometric parameters. In addition to known biometric parameters associated with pupillary block (narrower anterior biometric parameters-ACA, ACD, and AOD), our study found multiple nonpupillary block factors such as higher lens vault and thinner and more anteriorly placed ciliary body to be associated with APAC.

Indexed as

Glaucoma, Angle-ClosureAcute DiseaseAnterior Eye SegmentBiometryCiliary BodyCross-Sectional StudiesFemaleGonioscopyHumansIntraocular PressureMicroscopy, AcousticTomography, Optical CoherenceAcute primary angle closureanterior segment OCTaxial lengthocular biometric parametersretinochoroidal thicknessultrasound biomicroscopy

Identifiers

PMID35326023
PMCPMC9240576
OpenAlexW4220823029

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.