Evidence map›Paper›PMID 35325599›Full record

ArticleCurrent biology : CB2022

Pattern differentiation and tuning shift in human sensory cortex underlie long-term threat memory.

Yuqi You, Lucas R Novak, Kevin J Clancy, Wen Li

Open access · greenAbstract read
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Polygenic Risks for Depression and Neural Responses to Reward and Punishment in Young Adults.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Threat Memory in the Sensory Cortex: Insights from Olfaction.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Olfactory threat extinction in the piriform cortex: An age-dependent employment of NMDA receptor-dependent long-term depression.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuqi YouDepartment of Psychology, Florida State University, 1107 W. Call St., Tallahassee, FL 32306, USA. Electronic address: youlilly@gmail.com.
Lucas R NovakDepartment of Psychology, Florida State University, 1107 W. Call St., Tallahassee, FL 32306, USA.
Kevin J ClancyDepartment of Psychology, Florida State University, 1107 W. Call St., Tallahassee, FL 32306, USA.
Wen LiDepartment of Psychology, Florida State University, 1107 W. Call St., Tallahassee, FL 32306, USA. Electronic address: wenli@psy.fsu.edu.
Florida State University · US

Funding

Chemosensory Training Program (CTP)T32DC000044 · NIDCD · FLORIDA STATE UNIVERSITY · PI DEBRA Ann FADOOL · 1995 to 2026
$5.3M
Sensory Perception of Threat in AnxietyR01MH093413 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI LI, WEN · 2012 to 2016
$1.8M
Deficient inhibition underlies salience network hyperactivity in stress and anxietyR21MH126479 · NIMH · FLORIDA STATE UNIVERSITY · PI LI, WEN · 2022 to 2023
$425k
NIDCD NIH HHS T32 DC000044NIMH NIH HHS R01 MH093413NIMH NIH HHS R21 MH126479
6 · The paper itself

Abstract

The amygdala-prefrontal-cortex circuit has long occupied the center of the threat system,

Indexed as

Conditioning, ClassicalMemory, Long-TermAmygdalaHumansLearningMagnetic Resonance ImagingMemoryacquired associative representationsensory mechanisms of threat and anxietythreat memorythreat perceptionthreat processingthreat-related sensory cortical plasticitythreat representation

Identifiers

PMID35325599
PMCPMC9090975
OpenAlexW4221019370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.