Evidence map›Paper›PMID 35325548›Full record

ArticleJournal of computational biology : a journal of computational molecular cell biology2022

Integrating Long-Range Regulatory Interactions to Predict Gene Expression Using Graph Convolutional Networks.

Jeremy Bigness, Xavier Loinaz, Shalin Patel, Erica Larschan, Ritambhara Singh

Open access · greenAbstract read
In one paragraph

Article in Journal of computational biology : a journal of computational molecular cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. A Systematic Review of the Application of Graph Neural Networks to Extract Candidate Genes and Biological Associations.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2025
    Pooled it
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  7. Tokenization and deep learning architectures in genomics: A comprehensive review.Computational and structural biotechnology journal · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeremy BignessCenter for Computational Molecular Biology, Brown University, Providence, Rhode Island, USA.
Xavier LoinazDepartment of Computer Science, Brown University, Providence, Rhode Island, USA.
Shalin PatelDivision of Applied Mathematics, Brown University, Providence, Rhode Island, USA.
Erica LarschanCenter for Computational Molecular Biology, Brown University, Providence, Rhode Island, USA.
Ritambhara SinghCenter for Computational Molecular Biology, Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-7523-160X
Brown University · US

Funding

The role of Sirtuins in neurodegenerative diseaseP20GM109035 · NIGMS · BROWN UNIVERSITY · PI LIU, YAJUN · 2016 to 2025
$22.6M
Predoctoral Training Program in Biological Data Science at Brown UniversityT32GM128596 · NIGMS · BROWN UNIVERSITY · PI RAMACHANDRAN, SOHINI, SANDSTEDE, BJORN · 2018 to 2022
$1.5M
NIGMS NIH HHS P20 GM109035NIGMS NIH HHS T32 GM128596
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epigenesis, GeneticNeural Networks, ComputerGene ExpressionGenomeGenomicsHumansdeep learninggene expressiongraph neural networksHi-Chistone modifications

Identifiers

PMID35325548
PMCPMC9125570
OpenAlexW4221000785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.