Evidence map›Paper›PMID 35325472›Full record

ArticleActa anaesthesiologica Scandinavica2022

Perioperative prevention of persistent pain after total hip and knee arthroplasty-Protocol for two systematic reviews.

Jens Laigaard, Anders Karlsen, Mathias Maagaard, Lukas Kristian Rosenberg, Andreas Creutzburg, Troels Haxholdt Lunn, Ole Mathiesen, Søren Overgaard

Abstract read
In one paragraph

Article in Acta anaesthesiologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jens LaigaardDepartment of Anesthesiology, Centre for Anaesthesiological Research, Zealand University Hospital, Køge, Denmark.ORCID 0000-0001-5297-3769
Anders KarlsenDepartment of Anesthesiology, Centre for Anaesthesiological Research, Zealand University Hospital, Køge, Denmark.ORCID 0000-0002-0338-3751
Mathias MaagaardDepartment of Anesthesiology, Centre for Anaesthesiological Research, Zealand University Hospital, Køge, Denmark.ORCID 0000-0002-9037-7295
Lukas Kristian RosenbergDepartment of Orthopaedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0002-0535-6220
Andreas CreutzburgDepartment of Anaesthesia, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-3954-8634
Troels Haxholdt LunnDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Ole MathiesenDepartment of Anesthesiology, Centre for Anaesthesiological Research, Zealand University Hospital, Køge, Denmark.ORCID 0000-0003-4544-0619
Søren OvergaardDepartment of Orthopaedic Surgery and Traumatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0001-6829-4787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBetween 9% and 20% of patients experience moderate to severe persistent postoperative pain after total hip or knee arthroplasty. Severe immediate postoperative pain limits rehabilitation and is associated with the development of persistent postoperative pain. Therefore, perioperative analgesic and physiotherapeutic interventions are of interest to reduce persistent pain. In two systematic reviews with identical methodology, we aim to investigate the effects of (a) perioperative analgesic interventions and (b) physiotherapeutic interventions in reducing persistent pain after total hip and knee arthroplasty.

methodsWe will include randomised and cluster-randomised controlled trials on perioperative analgesic and physiotherapeutic interventions for patients undergoing elective total hip or knee arthroplasty for osteoarthritis. After contact with the authors, trials without pain data 3-24 months postoperatively will be excluded. Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase and reference lists will be searched for eligible trials. Two authors will independently screen, extract data and assess the risk of bias. The primary outcome is pain scores 3-24 months postoperatively. Meta-analyses will be performed for interventions with two or more trials. We will conduct trial sequential analyses and assign Grading of Recommendations, Assessment, Development and Evaluation (GRADE) ratings.

conclusionNo previous review on reduction of persistent postoperative pain has included non-pharmacological or invasive analgesic techniques. These two reviews with identical methodology will summarise the evidence of analgesic and physiotherapeutic perioperative interventions to prevent persistent pain. PROSPERO REGISTRATION: CRD42021284175.

Indexed as

Arthroplasty, Replacement, KneePostoperative PainAnalgesicsElective Surgical ProceduresHumansRandomized Controlled Trials as TopicSystematic Reviews as TopicAnalgesicschronic opioid therapychronic painclinical diversity in meta-analysespersistent postoperative painpersistent postsurgical painprotocolsystematic reviewtrial sequential analysis

Identifiers

PMID35325472
PMCPMC9315006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.