Evidence map›Paper›PMID 35325404›Full record

ArticleTissue engineering and regenerative medicine2022

Improvement of IgA Nephropathy and Kidney Regeneration by Functionalized Hyaluronic Acid and Gelatin Hydrogel.

Sureerat Khunmanee, So Young Chun, Yun-Sok Ha, Jun Nyung Lee, Bum Soo Kim, Wei-Wei Gao, In Yong Kim, Dong Keun Han, Seungkwon You, Tae Gyun Kwon and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering and regenerative medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Kidney-Derived ECM Hydrogels as Cell Delivery Devices.ACS applied materials & interfaces · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Sureerat Khunmanee *Department of Integrative Engineering, Chung-Ang University, 221 Heukseok-Dong, Dongjak-Gu, Seoul, 06974, Korea.
So Young Chun *BioMedical Research Institute, Kyungpook National University Hospital, Daegu, 41940, Korea.
Yun-Sok HaDepartment of Urology, Kyungpook National University Hospital, Daegu, 41944, Korea.
Jun Nyung LeeDepartment of Urology, Kyungpook National University Hospital, Daegu, 41944, Korea.
Bum Soo KimDepartment of Urology, Kyungpook National University Hospital, Daegu, 41944, Korea.
Wei-Wei GaoDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-go, Seoul, 02841, Korea.
In Yong KimDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-go, Seoul, 02841, Korea.
Dong Keun HanDepartment of Biomedical Science, College of Life Science, CHA University, 335 Pangyo-ro, Bundang-gu, Seongnam-si, Gyeonggi, 13488, Korea.
Seungkwon YouDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-go, Seoul, 02841, Korea.
Tae Gyun KwonDepartment of Urology, Kyungpook National University Chilgok Hospital, Daegu, 41404, Korea. tgkwon@knu.ac.kr.
Hansoo ParkDepartment of Integrative Engineering, Chung-Ang University, 221 Heukseok-Dong, Dongjak-Gu, Seoul, 06974, Korea. heyshoo@cau.ac.kr.
Korea University · KRKyungpook National University · KRKyungpook National University Hospital · KRCHA University · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunoglobulin A (IgA) nephropathy (IgAN) is one of an important cause of progressive kidney disease and occurs when IgA settles in the kidney resulted in disrupts kidney's ability to filter waste and excess water. Hydrogels are promising material for medical applications owing to their excellent adaptability and filling ability. Herein, we proposed a hyaluronic acid/gelatin (CHO-HA/Gel-NH

methodsCHO-HA/Gel-NH

resultsThe stiffness of the hydrogel was significantly enhanced and could be modulated by altering the concentrations and ratios of hydrogel. CHO-HA/Gel-NH

conclusionBased on in vivo studies, the renal regenerative ability of the progenitor cells could be further increased by this hydrogel system.

Indexed as

Glomerulonephritis, IGAHydrogelsAnimalsGelatinHyaluronic AcidImmunoglobulin AKidneyMiceRegenerationGelatinHyaluronic AcidHydrogelsImmunoglobulin AIgA nephropathyInjectable hydrogelUrine-derived renal progenitor cells

Identifiers

PMID35325404
PMCPMC9130434
OpenAlexW4221032987

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.