ReviewCurrent oncology reports2022
The Underestimated and Overlooked Burden of Diarrhea and Constipation in Cancer Patients.
Review in Current oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Experiences and coping strategies related to constipation among individuals with cancer: a qualitative study.BMC palliative care · 2026Article
- Impact of multi-channel follow-up as continuous nursing on cancer pain control, adverse reactions, and quality of life in patients with digestive tract tumors: a controlled study of 136 cases.Frontiers in oncology · 2026Article
- Microbiotoxicity: an under-recognised player in drug efficacy, toxicity, and health outcomes.npj antimicrobials and resistance · 2025Review
- Oncology's ongoing struggle with evaluating quality of life limiting, treatment-related toxicity.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Incidence and management of diarrhoea associated with abemaciclib and endocrine therapy for hormone-receptor positive, HER2-negative metastatic breast cancer: the UK patients' experiences.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Prediction of medication nonadherence in patients with lung cancer based on nomogram model construction.Medicine · 2025Observational
- Updated Interventions for Radiation-Induced Diarrhea: Putting Evidence Into Practice With the Oncology Nursing Society.Clinical journal of oncology nursing · 2025Review
- Low skeletal muscle density is a risk factor for constipation in patients on maintenance dialysis.Frontiers in physiology · 2025Article
- Nutritional risk, functional decline, and symptom burden in lung cancer: a study based on PG-SGA scores and biochemical data.Frontiers in nutrition · 2025Article
- Effect of Qigong exercise on quality of life and cortisol in patients with cancer: a non-randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Does the Argentine Tango Sustainably Improve Cancer-Associated Fatigue and Quality of Life in Breast Cancer Survivors?Cancers · 2023Article
- Age-related differences in the occurrence, severity, and distress of symptoms in older patients at the initiation of chemotherapy.BMC geriatrics · 2023Article
- Insights from Bacterial 16S rRNA Gene into Bacterial Genera and Predicted Metabolic Pathways Associated with Stool Consistency in Rectal Cancer Patients: A Proof of Concept.Biological research for nursing · 2023Article
- Factors Determining the Level of Acceptance of Illness and Satisfaction with Life in Patients with Cancer.Healthcare (Basel, Switzerland) · 2023Article
- Chemotherapy-associated oral microbiome changes in breast cancer patients.Frontiers in oncology · 2022Article
- Immune-mediated diarrhea and colitis with normal biochemical, endoscopic and histologic findings: a retrospective study.Annals of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review aims to summarize and discuss the diverse causes of two major gastrointestinal dysfunction symptoms, diarrhea and constipation, in cancer patients. We also discuss short- and long-term clinical, economic, and humanistic consequences, including the impact on cancer treatment regimens and patient quality of life, highlighting the limitations of the literature. RECENT
findingsDiarrhea and constipation as a result of cancer and its treatment can risk the success of anti-cancer therapies by requiring treatment delay or withdrawal, and imposes a substantial humanistic burden in patients with cancer. Despite its importance and frequency, gastrointestinal side effects may be overlooked due to the focus on cancer treatment, and the impact on patients may be underestimated. Additionally, the burden reported may not fully reflect current cancer management, particularly the true impact of economic consequences. A full understanding of the burden of diarrhea and constipation in patients with cancer is required, including broad evaluation of clinical considerations, the patient experience, and an updated assessment of economic burden. This would improve caregivers' appreciation of the impact of gastrointestinal dysfunction and aid the prioritization of future research efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.