Evidence map›Paper›PMID 35325274›Full record

ArticleApplied microbiology and biotechnology2022

The reliance of glycerol utilization by Cupriavidus necator on CO

Carl Simon Strittmatter, Jessica Eggers, Vanessa Biesgen, Inga Pauels, Florian Becker, Alexander Steinbüchel

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Article
  6. A Review on EnhancingFrontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Carl Simon StrittmatterInsitut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universtität Münster, Münster, Germany.ORCID http://orcid.org/0000-0003-0387-833X
Jessica EggersInsitut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universtität Münster, Münster, Germany.
Vanessa BiesgenInsitut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universtität Münster, Münster, Germany.ORCID http://orcid.org/0000-0001-9979-9905
Inga PauelsInsitut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universtität Münster, Münster, Germany.
Florian BeckerInsitut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universtität Münster, Münster, Germany.
Alexander SteinbüchelInsitut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universtität Münster, Münster, Germany. steinbu@uni-muenster.de.ORCID http://orcid.org/0000-0002-6189-834X
University of Münster · DEKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While crude glycerol is a cheap carbon source for industrial-scale cultivation of microorganisms, its application relies on fast growth and conversion. The biopolymer producing Cupriavidus necator H16 (synonym: Ralstonia eutropha H16) grows poorly on glycerol. The heterologous expression of glycerol facilitator glpF, glycerol kinase glpK, and glycerol dehydrogenase glpD from E. coli accelerated the growth considerably. The naturally occurring glycerol utilization is inhibited by low glycerol kinase activity. A limited heterotrophic growth promotes the dependency on autotrophic growth by carbon dioxide (CO

Indexed as

AquaporinsCupriavidus necatorEscherichia coli ProteinsCarbon DioxideEscherichia coliGlycerolGlycerol KinaseRibulose-Bisphosphate CarboxylaseAquaporinsCarbon DioxideEscherichia coli ProteinsGlpF protein, E coliGlycerolGlycerol KinaseRibulose-Bisphosphate CarboxylaseCalvin-Benson-Bassham cycleCarbon fixationCupriavidus necatorGlycerol utilizationMixotrophyRuBisCO activase CbbX

Identifiers

PMID35325274
OpenAlexW4221017956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.