ArticleSchizophrenia bulletin2022
Facial Emotion Recognition in Psychosis and Associations With Polygenic Risk for Schizophrenia: Findings From the Multi-Center EU-GEI Case-Control Study.
Article in Schizophrenia bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of Face Perception in Schizophrenia Spectrum Disorders: Evidence for Differential Impairment in Emotion Face Perception.Schizophrenia bulletin · 2024Pooled it
- Abnormal emotional intensity processing in individuals at clinical high risk for psychosis: evidence from event-related potentials.European archives of psychiatry and clinical neuroscience · 2026Article
- Facial emotion recognition, insight and social functioning in first episode psychosis: a cross-sectional study from an observational cohort.BMC psychiatry · 2026Observational
- Jumping to conclusions bias in early psychosis: Relationships with symptom dimensions, neurocognition and social cognition.Schizophrenia research. Cognition · 2026Article
- Differences in emotion recognition between nonimmersive versus immersive virtual reality: preliminary findings in schizophrenia and bipolar disorder.International clinical psychopharmacology · 2025Article
- Jumping to Conclusions and Facial Emotion Recognition in First-Episode Psychosis: Longitudinal Insights from the Gap Follow-Up Study.Clinical neuropsychiatry · 2025Article
- Moderation Effect of Emotional Expressivity on the Associations Between Schizotypal Traits, Autistic Traits and Social Pleasure.PsyCh journal · 2025Article
- Facial Emotion Recognition and its Associations With Psychological Well-Being Across Four Schizotypal Dimensions: a Cross-Sectional Study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Peripheral inflammation and neurocognitive functioning in early psychosis: Specific associations of TNF-α and IL-6 with social cognition.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Facial Emotion Recognition Ability in Individuals with Remitted Schizophrenia in Comparison to Healthy Population: A Cross-Sectional Study.Indian journal of psychological medicine · 2025Article
- Cerebral perfusion differences in the visual cortex and fusiform subregions across the psychosis spectrum.Frontiers in psychiatry · 2025Article
- Polygenic risk for major depression, attention deficit hyperactivity disorder, neuroticism, and schizophrenia are correlated with experience of intimate partner violence.Translational psychiatry · 2024Article
- Theory of mind in schizophrenia through a clinical liability approach: a sib-pair study.Frontiers in psychology · 2024Article
- Facial emotion-recognition deficits in patients with schizophrenia and unaffected first-degree relatives.Frontiers in psychiatry · 2024Article
- The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case-control study.Social psychiatry and psychiatric epidemiology · 2023Article
- Facial affect recognition in first-episode psychosis is impaired but not associated with psychotic symptoms.Heliyon · 2022Article
- COVID-19 and psychiatric disorders: The impact of face masks in emotion recognition face masks and emotion recognition in psychiatry.Frontiers in psychiatry · 2022Article
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39 authors.
Funding
Abstract
background and hypothesisFacial Emotion Recognition is a key domain of social cognition associated with psychotic disorders as a candidate intermediate phenotype. In this study, we set out to investigate global and specific facial emotion recognition deficits in first-episode psychosis, and whether polygenic liability to psychotic disorders is associated with facial emotion recognition. STUDY
design828 First Episode Psychosis (FEP) patients and 1308 population-based controls completed assessments of the Degraded Facial Affect Recognition Task (DFAR) and a subsample of 524 FEP and 899 controls provided blood or saliva samples from which we extracted DNA, performed genotyping and computed polygenic risk scores for schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MD). STUDY
resultsA worse ability to globally recognize facial emotion expressions was found in patients compared with controls [B= -1.5 (0.6), 95% CI -2.7 to -0.3], with evidence for stronger effects on negative emotions (fear [B = -3.3 (1.1), 95% CI -5.3 to -1.2] and anger [B = -2.3 (1.1), 95% CI -4.6 to -0.1]) than on happiness [B = 0.3 (0.7), 95% CI -1 to 1.7]. Pooling all participants, and controlling for confounds including case/control status, facial anger recognition was associated significantly with Schizophrenia Polygenic Risk Score (SZ PRS) [B = -3.5 (1.7), 95% CI -6.9 to -0.2].
conclusionsPsychosis is associated with impaired recognition of fear and anger, and higher SZ PRS is associated with worse facial anger recognition. Our findings provide evidence that facial emotion recognition of anger might play a role as an intermediate phenotype for psychosis.
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