SynthesisJournal of Crohn's & colitis2022
Systematic Review: The Impact and Importance of Body Composition in Inflammatory Bowel Disease.
Synthesis in Journal of Crohn's & colitis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Nutritional Status, Body Composition and Growth in Paediatric-Onset Ulcerative Colitis: A Systematic Review.Nutrients · 2026Pooled it
- Imaging-based assessment of body composition in patients with Crohn's disease: a systematic review.International journal of colorectal disease · 2023Pooled it
- Curcumin plus piperine improve body composition in patients with inflammatory bowel disease: a randomized, double-blind, placebo-controlled clinical trial.European journal of nutrition · 2025Trial
- Trial
- Nomogram for predicting 6-month BMIZ changes in children with Crohn's disease: a single-center retrospective study.BMC pediatrics · 2026Article
- Muscle Function Impairment in Crohn's Disease Patients: Risk Factors and Clinical Implications-Single-Tertiary-Center Experience.Life (Basel, Switzerland) · 2026Article
- The CT-based attenuation index of peri-bowel adipose tissue can predict disease progression in inflammatory bowel disease patients.European radiology · 2026Article
- Health-Related Physical Fitness in Patients With Inflammatory Bowel Disease vs Healthy Control Subjects.Inflammatory bowel diseases · 2025Article
- Factors Associated with Changes in Skeletal Muscle Mass in Medical Health Checkups.Journal of clinical medicine · 2025Article
- Gut, bone, and muscle: the triad of osteosarcopenia in inflammatory bowel disease.Intestinal research · 2025Review
- Corporal Composition and Gut Microbiome Modification Through Exclusion Dietary Intervention in Adult Patients with Crohn's Disease: Protocol for a Prospective, Interventional, Controlled, Randomized Clinical Trial.Journal of clinical medicine · 2025Article
- Increased CT Attenuation of Pericolic Adipose Tissue as a Noninvasive Marker of Disease Severity in Ulcerative Colitis.Korean journal of radiology · 2025Article
- Analysis of Body Composition and Levels of Antimicrobial Peptides in Patients with Basal Cell Carcinoma: A Preliminary Study.Journal of clinical medicine · 2025Article
- Dietary Profile of Patients with Inflammatory Bowel Disease in Clinical Remission-A Preliminary Study.Nutrients · 2024Article
- The association between hemoglobin level and sarcopenia in Chinese patients with Crohn's disease.BMC gastroenterology · 2024Article
- Computed tomography-based body composition parameters can predict short-term prognosis in ulcerative colitis patients.Insights into imaging · 2024Article
- Sarcopenia assessed by computed tomography or magnetic resonance imaging is associated with the loss of response to biologic therapies in adult patients with Crohn's disease.Clinical and translational science · 2023Article
- Preoperative screening and prehabilitation strategies prior to ileocolic resection in patients with Crohn's disease are not incorporated in routine care.International journal of colorectal disease · 2023Article
- Scoping review on health-related physical fitness in patients with inflammatory bowel disease: Assessment, interventions, and future directions.World journal of gastroenterology · 2023Article
- Body Composition Analysis in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease.Nutrients · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
Abstract
BACKGROUND AND
aimsAlterations in body composition are common in inflammatory bowel disease [IBD] and have been associated with differences in patient outcomes. We sought to consolidate knowledge on the impact and importance of body composition in IBD.
methodsWe performed a systematic search of MEDLINE, EMBASE and conference proceedings by combining two key research themes: inflammatory bowel disease and body composition.
resultsFifty-five studies were included in this review. Thirty-one focused on the impact of IBD on body composition with a total of 2279 patients with a mean age 38.4 years. Of these, 1071 [47%] were male. In total, 1470 [64.5%] patients had Crohn's disease and 809 [35.5%] had ulcerative colitis. Notably, fat mass and fat-free mass were reduced, and higher rates of sarcopaenia were observed in those with active IBD compared with those in clinical remission and healthy controls. Twenty-four additional studies focused on the impact of derangements in body composition on IBD outcomes. Alterations in body composition in IBD are associated with poorer prognoses including higher rates of surgical intervention, post-operative complications and reduced muscle strength. In addition, higher rates of early treatment failure and primary non-response are seen in patients with myopaenia.
conclusionsPatients with IBD have alterations in body composition parameters in active disease and clinical remission. The impacts of body composition on disease outcome and therapy are broad and require further investigation. The augmentation of body composition parameters in the clinical setting has the potential to improve IBD outcomes in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.