ArticlePloS one2022
Genomics of human and chicken Salmonella isolates in Senegal: Broilers as a source of antimicrobial resistance and potentially invasive nontyphoidal salmonellosis infections.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Antimicrobial resistance among clinical Enterobacterales isolated from humans in Senegal: a systematic review and meta-analysis from 1987 to 2022.BMC infectious diseases · 2026Pooled it
- Natural Products AgainstMicroorganisms · 2026Review
- Prevalence and molecular characterization of Salmonella spp. from clinical, food, and environmental sources in Addis Ababa and surrounding towns, Ethiopia.BMC microbiology · 2026Article
- Review
- Genomic Characterization ofMicroorganisms · 2026Article
- Antimicrobial Resistance in Selected Foodborne Pathogens in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2026Review
- Investigating the dynamics ofFrontiers in veterinary science · 2026Article
- A spotlight on multidrug-resistantFrontiers in microbiology · 2026Review
- Preliminary genomic characterisation and antimicrobial resistance of non-typhoidalFrontiers in microbiology · 2026Article
- A systematic review of antimicrobial resistance transmission inferences at the human-livestock interface in Africa.npj antimicrobials and resistance · 2025Article
- Supporting One Health policies to manage antibiotic resistance in Senegal: a systems analysis using group model building.Frontiers in public health · 2025Article
- Genomic characterization of antimicrobial-resistantFrontiers in microbiology · 2025Article
- Article
- Rare serovars of non-typhoidal Salmonella enterica isolated from humans, beef cattle and abattoir environments in Nigeria.PloS one · 2024Article
- Characterization ofFrontiers in microbiology · 2024Article
- Virulence gene profiles and antimicrobial susceptibility ofJournal of veterinary science · 2023Article
- Antimicrobial resistance and virulence genes of invasiveSAGE open medicine · 2023Article
- Antibiotic Resistance and Plasmid Replicon Types of Non-TyphoidalMicrobiology insights · 2023Article
- Invasive non-typhoidalFrontiers in microbiology · 2023Article
- One Health training needs for Senegalese professionals to manage emerging public health threats.Science in One Health · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
Salmonella enterica is the most common foodborne pathogen worldwide. It causes two types of diseases, a self-limiting gastroenteritis and an invasive, more threatening, infection. Salmonella gastroenteritis is caused by several serotypes and is common worldwide. In contrast, invasive salmonellosis is rare in high-income countries (HIC) while frequent in low- and middle-income countries (LMIC), especially in sub-Saharan Africa (sSA). Invasive Nontyphoidal Salmonella (iNTS), corresponding to serotypes other than Typhi and Paratyphi, have emerged in sSA and pose a significant risk to public health. We conducted a whole-genome sequence (WGS) analysis of 72 strains of Salmonella isolated from diarrheic human patients and chicken meat sold in multipurpose markets in Dakar, Senegal. Antimicrobial susceptibility testing combined with WGS data analysis revealed frequent resistance to fluoroquinolones and the sulfamethoxazole-trimethoprim combination that are among the most used treatments for invasive Salmonella. In contrast, resistance to the historical first-line drugs chloramphenicol and ampicillin, and to cephalosporins was rare. Antimicrobial resistance (AMR) was lower in clinical isolates compared to chicken strains pointing to the concern posed by the excessive use of antimicrobials in farming. Phylogenetic analysis suggested possible transmission of the emerging multidrug resistant (MDR) Kentucky ST198 and serotype Schwarzengrund from chicken to human. These results stress the need for active surveillance of Salmonella and AMR in order to address invasive salmonellosis caused by nontyphoidal Salmonella strains and other important bacterial diseases in sSA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.