Evidence map›Paper›PMID 35324991›Full record

ArticlePloS one2022

Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock.

Melike N Harfouche, Marta J Madurska, Noha Elansary, Hossam Abdou, Eric Lang, Joseph J DuBose, Rishi Kundi, David V Feliciano, Thomas M Scalea, Jonathan J Morrison

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Resuscitative endovascular balloon occlusion of the aorta in trauma patients: Past, present, and future.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Early experience with resuscitative endovascular balloon occlusion of the aorta for unstable pelvic fractures in the Republic of Korea: a multi-institutional study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Melike N HarfoucheR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.ORCID 0000-0001-9555-5698
Marta J MadurskaThe Freeman Hospital, Newcastle upon Tyne, United Kingdom.ORCID 0000-0001-5613-871X
Noha ElansaryR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.
Hossam AbdouR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.
Eric LangR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.
Joseph J DuBoseDell Medical School, University of Texas at Austin, Austin, Texas, United States of America.
Rishi KundiR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.
David V FelicianoR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.
Thomas M ScaleaR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.
Jonathan J MorrisonR Adams Cowley Shock Trauma Center, University of Maryland Medical System, Baltimore, Maryland, United States of America.ORCID 0000-0001-7462-8456
University of Maryland, Baltimore · USFreeman Hospital · GBThe University of Texas at Austin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is controversial as a hemorrhage control adjunct due to lack of data with a suitable control group. We aimed to determine outcomes of trauma patients in shock undergoing REBOA versus no-REBOA.

methodsThis single-center, retrospective, matched cohort study analyzed patients ≥16 years in hemorrhagic shock without cardiac arrest (2000-2019). REBOA (R; 2015-2019) patients were propensity matched 2:1 to historic (H; 2000-2012) and contemporary (C; 2013-2019) groups. In-hospital mortality and 30-day survival were analyzed using chi-squared and log rank testing, respectively.

resultsA total of 102,481 patients were included (R = 57, C = 88,545, H = 13,879). Propensity scores were assigned using age, race, mechanism, lowest systolic blood pressure, lowest Glasgow Coma Score (GCS), and body region Abbreviated Injury Scale scores to generate matched groups (R = 57, C = 114, H = 114). In-hospital mortality was significantly lower in the REBOA group (19.3%) compared to the contemporary (35.1%; p = 0.024) and historic (44.7%; p = 0.001) groups. 30-day survival was significantly higher in the REBOA versus no-REBOA groups.

conclusionIn a high-volume center where its use is part of a coordinated hemorrhage control strategy, REBOA is associated with improved survival in patients with noncompressible torso hemorrhage.

Indexed as

Balloon OcclusionEndovascular ProceduresShock, HemorrhagicAortaCohort StudiesHemorrhageHumansInjury Severity ScoreResuscitationRetrospective Studies

Identifiers

PMID35324991
PMCPMC8947416
OpenAlexW4220935908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.