ArticlePloS one2022
Burden of oral cancer in Asia from 1990 to 2019: Estimates from the Global Burden of Disease 2019 study.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Article
- Ultrasensitive detection of oral cancer biomarkers CD63 and CD44 in exosomes using janus particles: a rotational diffusometry-based assay.The Saudi dental journal · 2026Article
- Protacs in oral cancer: degrading oncogenic drivers for next-generation therapy.Frontiers in oral health · 2026Review
- Assessment of the Factors Influencing Early Detection Practices of Oral Carcinomas by Dentists: A Cross-Sectional Study.Oncology · 2026Article
- Preclinical validation of magnetic hyperthermia therapy for locally advanced oral cancer treatment.RSC advances · 2025Article
- Barriers to early diagnosis and treatment of oral cancer in countries in Africa: a scoping review.BMC oral health · 2025Article
- Global burden and regional inequalities of cancer in older adults from 1990 to 2021 and its projection until 2050.BMC public health · 2025Article
- Spatiotemporal Dynamics in the Burden of Lip and Oral Cavity Cancer and Attributable Risk Factors in Asia (1990-2021).Healthcare (Basel, Switzerland) · 2025Article
- Rural Pakistan's smokeless tobacco epidemic: a need for tailored interventions.BMC oral health · 2025Article
- Impact of Induction Chemotherapy Before Radical Chemoradiation in Oral Cavity Squamous Cell Carcinoma: A Tertiary Centre Experience.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005-2017.Heliyon · 2025Article
- Recent advances in biomarker detection of oral squamous cell carcinoma.Frontiers in oncology · 2025Review
- miRNA-199b-5p suppresses of oral squamous cell carcinoma by targeting apical-basolateral polarity via Scribble/Lgl.Molecular therapy. Nucleic acids · 2024Article
- A scientometric study of oral cancer research in South and Southeast Asia with emphasis on risk factors control.Journal of dental sciences · 2024Article
- Circulating mRNA Expression of VEGF, PTEN, and SOCS1 as Potential Prognostic Predictor for Nasopharyngeal Carcinoma Progression.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- The impact of vitamin D deficiency on caries, periodontitis, and oral cancer: A systematic review.The Saudi dental journal · 2024Review
- Article
- Temporal patterns of cancer burden in Asia, 1990-2019: a systematic examination for the Global Burden of Disease 2019 study.The Lancet regional health. Southeast Asia · 2024Article
- Exploring the Risk Factors for Oral Cancer in Pakistan: A Systematic Literature Review.Dentistry journal · 2024Review
- The mortality of oral cancer attributable to tobacco in China, the US, and India.Journal of cancer research and clinical oncology · 2023Article
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Abstract
backgroundOral cancer (OC) poses a threat to human health and imposes a heavy burden on countries. We assessed the burden imposed by OC on Asian nations from 1990 to 2019 based on gender and age.
methodsWe collected oral cancer data from the 2019 Global Burden of Disease study from 1990 to 2019 in 45 Asian countries and territories. Annual case data and age-standardised rates (ASRs) were used to investigate the incidence, mortality, and disability-adjusted life-years (DALYs) of OC based on age and gender from 1990 to 2019 in 45 Asian countries and territories. Estimated annual percentage changes (EAPCs) were used to assess incidence rate, mortality, and trends in DALYs.
resultsThe age-standardised incidence rate (ASIR) of OC increased from 1990 to 2019 with an EAPC of 0.32 (95% CI, 0.19-0.46), and the age-standardised death rate of OC remained stable at an EAPC of 0.08 (95%CI, from -0.06 to 0.21). The age-standardised DALYs of OC decreased at an EAPC of -0.16 (95%CI, from -0.30 to -0.02). The proportion of patients older than 70 years increased yearly in terms of incidence, mortality, and DALYs from 1990 to 2019. Of the DALYs, smoking was the main contributor in the Asian regions, and the largest contributor to DALYs in most Asian regions. Other contributors were alcohol use and chewing tobacco.
conclusionAlthough the burden of OC was declining in Asia, South Asia remained the region with the highest burden. OC caused the greatest burden in Pakistan, Taiwan China, and India. Therefore, measures should be taken to reduce the burden of oral cancer in high-risk regions and countries with attributable risk factors.
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