Evidence map›Paper›PMID 35324797›Full record

ReviewBioengineering (Basel, Switzerland)2022

Spinal Implant Osseointegration and the Role of 3D Printing: An Analysis and Review of the Literature.

Cameron Kia, Christopher L Antonacci, Ian Wellington, Heeren S Makanji, Sean M Esmende

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Application of custom-made joint prostheses in wrist.Journal of Zhejiang University. Science. B · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Cameron KiaDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.ORCID 0000-0002-5375-9868
Christopher L AntonacciDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.ORCID 0000-0002-9793-0524
Ian WellingtonDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.ORCID 0000-0002-6630-2939
Heeren S MakanjiBone and Joint Institute, Hartford Hospital, Hartford, CT 06106, USA.
Sean M EsmendeBone and Joint Institute, Hartford Hospital, Hartford, CT 06106, USA.
University of Connecticut · USHartford Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of interbody implants for spinal fusion has been steadily increasing to avoid the risks of complications and donor site morbidity when using autologous bone. Understanding the pros and cons of various implant designs can assist the surgeon in choosing the ideal interbody for each individual patient. The goal of these interbody cages is to promote a surface area for bony ingrowth while having the biomechanical properties to support the axial skeleton. Currently, the majority of interbody implants consists of metal or polyether ether ketone (PEEK) cages with bone graft incorporated inside. Titanium alloy implants have been commonly used, however, the large difference in modulus of elasticity from bone has inherent issues. PEEK implants have a desirable surface area with the benefit of a modulus of elasticity closer to that of bone. Unfortunately, clinically, these devices have had increased risk of subsidence. More recently, 3D printed implants have come into the market, providing mechanical stability with increased surface design for bony ingrowth. While clinical outcomes studies are limited, early results have demonstrated more reliable and quicker fusion rates using 3D custom interbody devices. In this review, we discuss the biology of osseointegration, the use of surface coated implants, as well as the potential benefits of using 3D printed interbodies.

Indexed as

3D printingfusioninterbodyorthopedicsspine

Identifiers

PMID35324797
PMCPMC8944949
OpenAlexW4221047601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.