ArticleBioengineering (Basel, Switzerland)2022
Distensibility of Deformable Aortic Replicas Assessed by an Integrated In-Vitro and In-Silico Approach.
Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- An Experimental Measurement Method to Characterize and Apply Platinum Silicon Material for a Biomechanical Replica of the Thoracic Aorta.Biomimetics (Basel, Switzerland) · 2026Article
- Mechanical testing and comparison of porcine tissue, silicones and 3D-printed materials for cardiovascular phantoms.Frontiers in bioengineering and biotechnology · 2023Article
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5 authors.
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Abstract
The correct estimation of the distensibility of deformable aorta replicas is a challenging issue, in particular when its local characterization is necessary. We propose a combined in-vitro and in-silico approach to face this problem. First, we tested an aortic silicone arch in a pulse-duplicator analyzing its dynamics under physiological working conditions. The aortic flow rate and pressure were measured by a flow meter at the inlet and two probes placed along the arch, respectively. Video imaging analysis allowed us to estimate the outer diameter of the aorta in some sections in time. Second, we replicated the in-vitro experiment through a Fluid-Structure Interaction simulation. Observed and computed values of pressures and variations in aorta diameters, during the cardiac cycle, were compared. Results were considered satisfactory enough to suggest that the estimation of local distensibility from in-silico tests is reliable, thus overcoming intrinsic experimental limitations. The aortic distensibility (
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