Evidence map›Paper›PMID 35324774›Full record

ArticleBioengineering (Basel, Switzerland)2022

Impacts of Resveratrol and Pyrogallol on Physicochemical, Mechanical and Biological Properties of Epoxy-Resin Sealers.

Naji Kharouf, Salvatore Sauro, Louis Hardan, Amr Fawzi, Ilona Eveline Suhanda, Jihed Zghal, Frédéric Addiego, Christine Affolter-Zbaraszczuk, Youri Arntz, Vincent Ball and 3 more

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 6 countries.

Naji KharoufDepartment of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, Université de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0001-6768-138X
Salvatore SauroDental Biomaterials and Minimally Invasive Dentistry, Department of Dentistry, Cardenal Herrera-CEU University, CEU Universities, C/Santiago Ramón y Cajal, s/n., Alfara del Patriarca, 46115 Valencia, Spain.ORCID 0000-0002-2527-8776
Louis HardanDepartment of Restorative Dentistry, Saint-Joseph University, Beirut 11072180, Lebanon.ORCID 0000-0001-8577-2285
Amr FawziUWA Dental School, University of Western Australia, Nedlands, WA 6009, Australia.ORCID 0000-0001-6357-0535
Ilona Eveline SuhandaDepartment of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, Université de Strasbourg, 67000 Strasbourg, France.
Jihed ZghalICube Laboratory, UMR 7357 CNRS, Mechanics Department, University of Strasbourg, 67000 Strasbourg, France.ORCID 0000-0002-5019-7177
Frédéric AddiegoLuxembourg Institute of Science and Technology (LIST), Department Materials Research and Technology (MRT), ZAE Robert Steichen, 5 rue Bommel, L-4940 Hautcharage, Luxembourg.ORCID 0000-0002-4081-9526
Christine Affolter-ZbaraszczukInstitut National de la Santé et de la Recherche Médicale, INSERM UMR_S 1121 Biomaterials and Bioengineering, 67085 Strasbourg, France.
Youri ArntzDepartment of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, Université de Strasbourg, 67000 Strasbourg, France.
Vincent BallDepartment of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, Université de Strasbourg, 67000 Strasbourg, France.
Florent MeyerDepartment of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, Université de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0002-5275-3421
Youssef HaikelDepartment of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, Université de Strasbourg, 67000 Strasbourg, France.
Davide MancinoDepartment of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, Université de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0001-7376-371X
Inserm · FRCentre National de la Recherche Scientifique · FRLuxembourg Institute of Science and Technology · LUSaint Joseph University · LBSechenov University · RUThe University of Western Australia · AUUniversité de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed at evaluating the physicochemical and biological properties of experimental epoxy-resin sealers containing polyphenols such as resveratrol and pyrogallol. A conventional epoxy resin (OB) was modified by adding different concentrations of resveratrol (RS) or pyrogallol (PY) to its composition. Antibacterial and antioxidant activities, mechanical properties, along with wettability and morphological changes were investigated. The results were statistically analyzed using ANOVA and multiple comparison tests (α = 0.05). The incorporation of the tested polyphenols into the epoxy resin enhanced its mechanical properties. PY demonstrated much better antioxidant and antibacterial activities than RS, which were associated with a higher release of PY. In contrast, PY showed a higher cytotoxicity than OB and OB doped with RS. OB containing PY presented a rougher surface and higher water absorption than OB doped with RS. Both tested polyphenols caused no notable changes to the overall porosity of OB. Resveratrol and pyrogallol may not only influence the morphology and mechanical properties of epoxy-resin sealers, but could also enhance antioxidant activity and antibacterial effects against

Indexed as

biological activityendodontic sealerpolyphenolspyrogallolresveratrol

Identifiers

PMID35324774
PMCPMC8945518
OpenAlexW4214773186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.