Evidence map›Paper›PMID 35324710›Full record

ReviewToxins2022

Determination of Cyanotoxins and Prymnesins in Water, Fish Tissue, and Other Matrices: A Review.

Devi Sundaravadivelu, Toby T Sanan, Raghuraman Venkatapathy, Heath Mash, Dan Tettenhorst, Lesley DAnglada, Sharon Frey, Avery O Tatters, James Lazorchak

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Devi SundaravadiveluPegasus Inc., U.S. EPA, Cincinnati, OH 45268, USA.ORCID 0000-0002-7787-035X
Toby T SananOffice of Research and Development, Center for Environmental Solutions and Emergency Response, U.S. EPA, Cincinnati, OH 45268, USA.ORCID 0000-0002-0186-2089
Raghuraman VenkatapathyPegasus Inc., U.S. EPA, Cincinnati, OH 45268, USA.
Heath MashOffice of Research and Development, Center for Environmental Solutions and Emergency Response, U.S. EPA, Cincinnati, OH 45268, USA.
Dan TettenhorstOffice of Research and Development, Center for Environmental Solutions and Emergency Response, U.S. EPA, Cincinnati, OH 45268, USA.
Lesley DAngladaOffice of Water, Science and Technology, U.S. EPA, Washington, DC 20004, USA.
Sharon FreyOffice of Water, Science and Technology, U.S. EPA, Washington, DC 20004, USA.
Avery O TattersCenter for Environmental Measurement and Modeling, U.S. EPA, Gulf Breeze, FL 32561, USA.
James LazorchakCenter for Environmental Measurement and Modeling, U.S. EPA, Cincinnati, OH 45268, USA.ORCID 0000-0002-7354-7571
Environmental Protection Agency · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Harmful algal blooms (HABs) and their toxins are a significant and continuing threat to aquatic life in freshwater, estuarine, and coastal water ecosystems. Scientific understanding of the impacts of HABs on aquatic ecosystems has been hampered, in part, by limitations in the methodologies to measure cyanotoxins in complex matrices. This literature review discusses the methodologies currently used to measure the most commonly found freshwater cyanotoxins and prymnesins in various matrices and to assess their advantages and limitations. Identifying and quantifying cyanotoxins in surface waters, fish tissue, organs, and other matrices are crucial for risk assessment and for ensuring quality of food and water for consumption and recreational uses. This paper also summarizes currently available tissue extraction, preparation, and detection methods mentioned in previous studies that have quantified toxins in complex matrices. The structural diversity and complexity of many cyanobacterial and algal metabolites further impede accurate quantitation and structural confirmation for various cyanotoxins. Liquid chromatography-triple quadrupole mass spectrometer (LC-MS/MS) to enhance the sensitivity and selectivity of toxin analysis has become an essential tool for cyanotoxin detection and can potentially be used for the concurrent analysis of multiple toxins.

Indexed as

Cyanobacteria ToxinsWaterAnimalsChromatography, LiquidEcosystemFishesHarmful Algal BloomMicrocystinsTandem Mass SpectrometryCyanobacteria ToxinsMicrocystinsWatercyanobacteriacyanotoxinsdetection methodsfish tissueharmful algal bloomsshellfish

Identifiers

PMID35324710
PMCPMC8949488
OpenAlexW4220768789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.