Evidence map›Paper›PMID 35324709›Full record

ArticleToxins2022

Analysis of Active Compounds Using Target Protein Cofilin-Cucurbitacins in Cytotoxic Plant

Souichi Nakashima, Yoshimi Oda, Moeko Morita, Ayako Ohta, Toshio Morikawa, Hisashi Matsuda, Seikou Nakamura

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Souichi NakashimaDepartment of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan.ORCID 0000-0001-7588-0784
Yoshimi OdaDepartment of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan.
Moeko MoritaDepartment of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan.
Ayako OhtaDepartment of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan.
Toshio MorikawaPharmaceutical Research and Technology Institute, Kindai University, Osaka 577-8502, Japan.ORCID 0000-0003-2794-5365
Hisashi MatsudaDepartment of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan.
Seikou NakamuraDepartment of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan.ORCID 0000-0003-3172-299X
Kyoto Pharmaceutical University · JPKindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined a two-step target protein binding strategy that uses cofilin as the target protein to analyze the active constituents in

Indexed as

Antineoplastic AgentsBryoniaActin Depolymerizing FactorsCell ProliferationCucurbitacinsHumansPlant ExtractsPlantsActin Depolymerizing FactorsAntineoplastic AgentsCucurbitacinsPlant Extractscofilincucurbitacinisocucurbitacin Disolation with target protein

Identifiers

PMID35324709
PMCPMC8955846
OpenAlexW4220722646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.