Evidence map›Paper›PMID 35324593›Full record

ArticleTropical medicine and infectious disease2022

Analysis of

Emmanuel Kabwe, Walaa Al Sheikh, Anton F Shamsutdinov, Ruzilya K Ismagilova, Ekaterina V Martynova, Olesia V Ohlopkova, Yuri A Yurchenko, Tatiana A Savitskaya, Guzel S Isaeva, Svetlana F Khaiboullina and 3 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Emmanuel KabweOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0003-4328-8190
Walaa Al SheikhOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Anton F ShamsutdinovOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Ruzilya K IsmagilovaOpenLab "Omics Technology", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Ekaterina V MartynovaOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Olesia V OhlopkovaState Research Center of Virology and Biotechnology "Vector", Rospotrebnadzor, World-Class Genomic Research Center for Biological Safety and Technological Independence, Federal Scientific and Technical Program on the Development of Genetic Technologies, 630559 Koltsovo, Russia.
Yuri A YurchenkoHygienic and Epidemiological Center for Novosibirsk Region, 630099 Novosibirsk, Russia.
Tatiana A SavitskayaKazan Research Institute of Epidemiology and Microbiology, 420012 Kazan, Russia.
Guzel S IsaevaKazan Research Institute of Epidemiology and Microbiology, 420012 Kazan, Russia.
Svetlana F KhaiboullinaOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Albert A RizvanovOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0002-9427-5739
Sergey P MorzunovOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Yuriy N DavidyukOpenLab "Gene and Cell Technologies ", Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0002-4409-2942
Kazan Federal University · RUKazan Research Institute of Epidemiology and Microbiology · RUInstitute of Systematics and Ecology of Animals · RUState Research Center of Virology and Biotechnology VECTOR · RUUniversity of Nevada, Reno · US

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2019-1665Russian Foundation for Basic Research 19-34-60012
6 · The paper itself

Abstract

Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease commonly diagnosed in the Volga Federal District (VFD). HFRS is caused by Puumala orthohantavirus (PUUV), and this virus is usually detected in bank voles as its natural host (Myodes glareolus). The PUUV genome is composed of the single-stranded, negative-sense RNA containing three segments. The goal of the current study is to identify genome variants of PUUV strains circulating in bank voles captured in the Udmurt Republic (UR) and Ulyanovsk region (ULR). The comparative and phylogenetic analysis of PUUV strains revealed that strains from Varaksino site UR are closely related to strains previously identified in the Pre-Kama area of the Republic of Tatarstan (RT), whilst strains from Kurlan and Mullovka sites ULR are similar to strains from the Trans-Kama area of the RT. It was also found that Barysh ULR strains form a separate distinct group phylogenetically equidistant from Varaksino and Kurlan−Mullovka groups. The identified groups of strains can be considered as separate sub-lineages in the PUUV Russian genetic lineage. In addition, the genomes of the strains from the UR, most likely, were formed as a result of reassortment.

Indexed as

genetic variabilityphylogenetic analysisPuumala orthohantavirus genomereassortation

Identifiers

PMID35324593
PMCPMC8952242
OpenAlexW4220999898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.