Evidence map›Paper›PMID 35324427›Full record

ArticleeLife2022

STIMulating blood pressure.

Tessa A C Garrud, Jonathan H Jaggar

Abstract readComment
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Tessa A C GarrudDepartment of Physiology, University of Tennessee Health Science Center, Memphis, United States.ORCID 0000-0002-7900-7939
Jonathan H JaggarDepartment of Physiology, University of Tennessee Health Science Center, Memphis, United States.ORCID 0000-0003-1505-3335

Funding

SK3 channel trafficking in endothelial cellsR01HL158846 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JAGGAR, JONATHAN H · 2021 to 2024
$2.5M
PKD proteins in endothelial cellsR01HL155180 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JAGGAR, JONATHAN H · 2021 to 2024
$2.4M
Blood pressure regulation by smooth muscle cell ion channelsR01HL133256 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JAGGAR, JONATHAN H · 2017 to 2020
$1.5M
NHLBI NIH HHS R01 HL133256NHLBI NIH HHS R01 HL155180NHLBI NIH HHS R01 HL158846
6 · The paper itself

Abstract

The protein STIM1 helps to maintain membrane coupling sites in smooth muscle cells that regulate arterial contractility and blood pressure.

Indexed as

Calcium SignalingMuscle, Smooth, VascularBlood PressureMyocytes, Smooth MuscleStromal Interaction Molecule 1Stromal Interaction Molecule 1blood pressuremolecular biophysicsmouseperipheral coupling sitessmooth muscleSTIM1store-operated calcium entryStromal Interaction Moleculesstructural biology

Identifiers

PMID35324427
PMCPMC8947758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.