Evidence map›Paper›PMID 35323948›Full record

ArticleJAMA network open2022

Rates of Diabetes-Related Major Amputations Among Racial and Ethnic Minority Adults Following Medicaid Expansion Under the Patient Protection and Affordable Care Act.

Tze-Woei Tan, Elizabeth A Calhoun, Shannon M Knapp, Adelina I Lane, David G Marrero, C Kent Kwoh, Wei Zhou, David G Armstrong

Open access · goldAbstract read
In one paragraph

Article in JAMA network open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. The Affordable Care Act Improves Access, Survival, and Racial Disparities of Patients With Liver Disease: A Systematic Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Evaluation and Management of Diabetes-related Foot Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. The conundrum of diabetic neuropathies-Past, present, and future.Journal of diabetes and its complications · 2022
    Review
  15. Racial/ethnic disparities in chronic wounds: Perspectives on linking upstream factors to health outcomes.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tze-Woei TanDepartment of Surgery, University of Arizona College of Medicine, Tucson.
Elizabeth A CalhounDepartment of Population Health, University of Kansas Medical Center, Kansas City.
Shannon M KnappStatistics Consulting Lab, Bio5 Institute, University of Arizona, Tucson.
Adelina I LaneDepartment of Surgery, University of Arizona College of Medicine, Tucson.
David G MarreroCenter for Border Health Disparities, University of Arizona Health Science, Tucson.
C Kent KwohDepartment of Medicine, University of Arizona College of Medicine, Tucson.
Wei ZhouDepartment of Surgery, University of Arizona College of Medicine, Tucson.
David G ArmstrongSouthwestern Academic Limb Salvage Alliance (SALSA), Los Angeles, California.
University of Arizona · USUniversity of Kansas Medical Center · USUniversity of Southern California · US

Funding

New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Targeting Epigenomic Regulators at the Replication Fork in PDACR01CA247898 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI LOMBERK, GWEN · 2021 to 2025
$2.3M
Improving the science of adherence reinforcement and safe mobility in people with diabetic foot ulcers using smart offloadingR01DK124789 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARMSTRONG, DAVID GEORGE, NAJAFI, BIJAN · 2021 to 2025
$2.0M
Determinants in Limb Preservation in Hispanics and Native AmericansK23DK122126 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TAN, TZE-WOEI · 2019 to 2023
$845k
NCI NIH HHS R01 CA247898NIDDK NIH HHS K23 DK122126NIDDK NIH HHS P30 DK111022NIDDK NIH HHS R01 DK124789
6 · The paper itself

Abstract

Importance: It is not known whether implementation of Medicaid expansion under the Patient Protection and Affordable Care Act (ACA) was associated with improvements in the outcomes among racial and ethnic minority adults at risk of diabetes-related major amputations. Objective: To explore the association of early Medicaid expansion with outcomes of diabetic foot ulcerations (DFUs). Design, Setting, and Participants: This cohort study included hospitalizations for DFUs among African American, Asian and Pacific Islander, American Indian or Alaska Native, and Hispanic adults as well as adults with another minority racial or ethnic identification aged 20 to 64 years. Data were collected from the State Inpatient Databases for 19 states and the District of Columbia for 2013 to the third quarter of 2015. The analysis was performed on December 4, 2019, and updated on November 9, 2021. Exposures: States were categorized into early-adopter states (expansion by January 2014) and nonadopter states. Main Outcomes and Measures: Poisson regression was performed to examine the associations of state type, time, and their combined association with the proportional changes of major amputation rate per year per 100 000 population. Results: Among the 115 071 hospitalizations among racial and ethnic minority adults with DFUs (64% of sample aged 50 to 64 years; 35%, female; 61%, African American; 25%, Hispanic; 14%, other racial and ethnic minority group), there were 36 829 hospitalizations (32%) for Medicaid beneficiaries and 10 500 hospitalizations (9%) for uninsured patients. Hospitalizations increased 3% (95% CI, 1% to 5%) in early-adopter states and increased 8% (95% CI, 6% to 10%) in nonadopter states after expansion, a significant difference (P for interaction < .001). Although there was no change in the amputation rate (0.08%; 95% CI, -6% to 7%) in early-adopter states after expansion, there was a 9% (95% CI, 3% to 16%) increase in nonadopter states, a significant change (P = .04). For uninsured adults, the amputation rate decreased 33% (95% CI, 10% to 50%) in early-adopter states and did not change (12%; 95% CI, -10% to 38%) in nonadopter states after expansion, a significant difference (P = .006). There was no difference in the change of amputation rate among Medicaid beneficiaries between state types after expansion. Conclusions and Relevance: This study found a relative improvement in the major amputation rate among African American, Hispanic, and other racial and ethnic minority adults in early-expansion states compared with nonexpansion states, which could be because of the recruitment of at-risk uninsured adults into the Medicaid program during the first 2 years of ACA implementation. Future study is required to evaluate the long-term association of Medicaid expansion and the rates of amputation.

Indexed as

Diabetes MellitusPatient Protection and Affordable Care ActAdultAmputation, SurgicalCohort StudiesEthnic and Racial MinoritiesEthnicityFemaleHumansInsurance CoverageMaleMedicaidMinority GroupsUnited States

Identifiers

PMID35323948
PMCPMC8948528
OpenAlexW4220928164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.