Evidence map›Paper›PMID 35323703›Full record

ArticleMetabolites2022

Broadband-NIRS System Identifies Epileptic Focus in a Child with Focal Cortical Dysplasia-A Case Study.

Aikaterini Vezyroglou, Peter Hebden, Isabel De Roever, Rachel Thornton, Subhabrata Mitra, Alan Worley, Mariana Alves, Emma Dean, Judith Helen Cross, Ilias Tachtsidis

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Aikaterini VezyroglouDevelopmental Neurosciences, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.ORCID 0000-0001-6495-0863
Peter HebdenMedical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UK.
Isabel De RoeverMedical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UK.
Rachel ThorntonDepartment of Clinical Neurophysiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
Subhabrata MitraNeonatology, EGA Institute for Women's Health, University College London, London W1T 7NF, UK.ORCID 0000-0002-4304-4594
Alan WorleyDepartment of Clinical Neurophysiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
Mariana AlvesDepartment of Clinical Neurophysiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
Emma DeanDepartment of Clinical Neurophysiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
Judith Helen CrossDevelopmental Neurosciences, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.ORCID 0000-0001-7345-4829
Ilias TachtsidisMedical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UK.ORCID 0000-0002-8125-0313
Great Ormond Street Hospital for Children NHS Foundation Trust · GBUniversity College London · GBGreat Ormond Street Hospital · GB

Funding

Great Ormond Street Hospital Children's Charity V0118Medical Research Council MR/S003134/1Wellcome Trust 219610/Z/19/Z
6 · The paper itself

Abstract

Epileptic seizures are transiently occurring symptoms due to abnormal excessive or synchronous neuronal activity in the brain. Previous functional near-infrared spectroscopy (fNIRS) studies during seizures have focused in only monitoring the brain oxygenation and haemodynamic changes. However, few tools are available to measure actual cellular metabolism during seizures, especially at the bedside. Here we use an in-house developed multichannel broadband NIRS (or bNIRS) system, that, alongside the changes in oxy-, deoxy- haemoglobin concentration (HbO

Indexed as

brain injurybrain metabolismbroadband Near Infrared Spectroscopy (bNIRS)paediatric epilepsyseizures

Identifiers

PMID35323703
PMCPMC8951122
OpenAlexW4220661406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.