Evidence map›Paper›PMID 35323689›Full record

ArticleMetabolites2022

Secondary Metabolites of Actinomycetales as Potent Quorum Sensing Inhibitors Targeting Gram-Positive Pathogens: In Vitro and In Silico Study.

Said E Desouky, Mohammed Abu-Elghait, Eman A Fayed, Samy Selim, Basit Yousuf, Yasuhiro Igarashi, Basel A Abdel-Wahab, Amnah Mohammed Alsuhaibani, Kenji Sonomoto, Jiro Nakayama

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  7. Why Do FilamentousAnnual review of microbiology · 2025
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  11. Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targetingJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
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  14. Norwogonin aids in fighting MRSA-induced pneumonia by targeting agrAWorld journal of microbiology & biotechnology · 2024
    Article
  15. Article
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  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Said E DesoukyDepartment of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt.
Mohammed Abu-ElghaitDepartment of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0001-9007-1029
Eman A FayedDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt.ORCID 0000-0002-4579-5180
Samy SelimDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-4025-8586
Basit YousufLaboratory of Microbial Technology, Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.ORCID 0000-0002-3452-8749
Yasuhiro IgarashiBiotechnology Research Center, Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.
Basel A Abdel-WahabDepartment of Medical Pharmacology, College of Medicine, Assiut University, Assiut 7111, Egypt.ORCID 0000-0002-5545-6422
Amnah Mohammed AlsuhaibaniDepartment of Physical Sport Science, College of Education, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0002-8299-1906
Kenji SonomotoLaboratory of Microbial Technology, Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Jiro NakayamaLaboratory of Microbial Technology, Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Kyushu University · JPAl-Azhar University · EGJouf University · SANajran University · SAPrincess Nourah bint Abdulrahman University · SAToyama Prefectural University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-virulence agents are non-bacteriostatic and non-bactericidal emerging therapeutic options which hamper the production of virulence factors in pathogenic flora. In

Indexed as

actinomycetales metabolitesagr systemanti-virulence compoundsEnterococcus faecalisfsr systemmolecular dockingquorum sensing inhibitorquorum sensing systemStaphylococcus aureus

Identifiers

PMID35323689
PMCPMC8955454
OpenAlexW4220676772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.