Evidence map›Paper›PMID 35323677›Full record

ArticleMetabolites2022

Association between Smoking and Urine Indole Levels Measured by a Commercialized Test.

Masataka Mine, Nobuyuki Masaki, Takumi Toya, Takayuki Namba, Yuji Nagatomo, Bonpei Takase, Takeshi Adachi

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Masataka MineJapan Air Self-Defense Force Aeromedical Laboratory, Sayama 350-1324, Japan.
Nobuyuki MasakiDepartment of Intensive Care Medicine, National Defense Medical College, Tokorozawa 359-8513, Japan.ORCID 0000-0002-4426-3692
Takumi ToyaDepartment of Intensive Care Medicine, National Defense Medical College, Tokorozawa 359-8513, Japan.ORCID 0000-0002-4681-2798
Takayuki NambaDepartment of Cardiology, National Defense Medical College, Tokorozawa 359-8513, Japan.
Yuji NagatomoDepartment of Cardiology, National Defense Medical College, Tokorozawa 359-8513, Japan.ORCID 0000-0002-3430-4614
Bonpei TakaseDepartment of Intensive Care Medicine, National Defense Medical College, Tokorozawa 359-8513, Japan.
Takeshi AdachiDepartment of Cardiology, National Defense Medical College, Tokorozawa 359-8513, Japan.
National Defense Medical College · JPSelf-Defense Forces Central Hospital · JP

Funding

Ministry of Education, Science, and Culture of Japan 20K08503
6 · The paper itself

Abstract

Indoles are formed from dietary tryptophan by tryptophanase-positive bacterium. A few amounts of indole are excreted in the urine. On the other hand, cigarette smoke contains indoles, which could also change the urine indole levels. This study sought to elucidate the relationship between urine indole levels and smoking habits. A total of 273 healthy men (46 ± 6 years old) were enrolled in the study. Fasting urine and blood samples were obtained in the morning. The indole concentration was measured by a commercialized kit with a modified Kovac's reagent. The relationship with smoking status was evaluated. The median value of the urine indole test was 29.2 mg/L (interquartile range; 19.6-40.8). The urine indole level was significantly elevated in the smoking subjects (non-smoking group, 28.9 (20.9-39.1) mg/L,

Indexed as

clinical studiesindolemetabolismsmoking

Identifiers

PMID35323677
PMCPMC8950635
OpenAlexW4220840050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.