Evidence map›Paper›PMID 35323661›Full record

ArticleMetabolites2022

Microbiome, Mycobiome and Related Metabolites Alterations in Patients with Metabolic Syndrome-A Pilot Study.

Gratiela Gradisteanu Pircalabioru, Iuliana Ilie, Luciana Oprea, Ariana Picu, Laura Madalina Petcu, Liliana Burlibasa, Mariana-Carmen Chifiriuc, Madalina Musat

Abstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
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  6. Review
  7. Article
  8. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Epidemiology of the COVID-19 pneumonia in a group of hospitals from Madrid-Spain during the full period of the State of Alarm HM cohort.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Observational
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. The Role of the Mycobiome in Women's Health.Journal of fungi (Basel, Switzerland) · 2023
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gratiela Gradisteanu PircalabioruResearch Institute of University of Bucharest (ICUB), 050095 Bucharest, Romania.
Iuliana IlieGral Medical Clinic, 031424 Bucharest, Romania.ORCID 0000-0001-6659-3417
Luciana OpreaNational Institute of Endocrinology C.I. Parhon, 011863 Bucharest, Romania.ORCID 0000-0002-1200-9518
Ariana PicuResearch Institute of University of Bucharest (ICUB), 050095 Bucharest, Romania.
Laura Madalina PetcuResearch Institute of University of Bucharest (ICUB), 050095 Bucharest, Romania.
Liliana BurlibasaFaculty of Biology, University of Bucharest, 050095 Bucharest, Romania.ORCID 0000-0003-0596-9331
Mariana-Carmen ChifiriucResearch Institute of University of Bucharest (ICUB), 050095 Bucharest, Romania.ORCID 0000-0001-6098-1857
Madalina MusatNational Institute of Endocrinology C.I. Parhon, 011863 Bucharest, Romania.

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii CNFIS-FDI-2021-0405Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P1-1.1-36PD-2019-0499
6 · The paper itself

Abstract

Metabolic syndrome (MetSyn) has a rapidly growing worldwide prevalence, affecting over 1 billion people. MetSyn is clustering many pathological conditions, which, untreated, could increase the risk and often lead to more severe metabolic defects such as type 2 diabetes and non-alcoholic fatty liver disease. Many data demonstrate the complex role of gut microbiota in the host metabolism, and hence, deciphering the microbiome patterns linked to MetSyn could enable us for novel diagnosis and monitoring markers and for better disease management. Moreover, interventions designed to alter patient microbiome composition may help prevent or decrease morbidity linked with MetSyn. However, the microbiome composition is largely different across geographically distinct populations. Our study investigated the microbiota and mycobiome patterns in Romanian metabolic syndrome patients. We also correlated the identified microbiome-mycobiome patterns with levels of metabolites important for host health such as short chain fatty acids, organic acids, and taurine. We found that MetSyn patients are harboring a microbiome enriched in

Indexed as

metabolic syndromemetabolomemicrobiomemicrobiotamycobiome

Identifiers

PMID35323661
PMCPMC8951583

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.