ArticleJournal of cardiovascular development and disease2022
Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up.
Article in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06464042 (Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease
Who cites it
14 citing papers in PubMed.
- Synergistic Effects of Diabetes, Inflammatory/Coagulopathy Biomarkers, TG and Hypoxic Stress on Premature Coronary Heart Disease in High-Altitude Populations.Journal of cardiovascular development and disease · 2026Article
- Stress CT myocardial perfusion imaging after arterial switch operation for transposition of the great arteries.European heart journal. Imaging methods and practice · 2026Article
- Metabolic risk factors associated with premature myocardial infarction in adults ≤ 35 years: a case-control study.BMC cardiovascular disorders · 2026Article
- Clinical and angiographic characteristics of very young patients undergoing invasive coronary angiography.Frontiers in cardiovascular medicine · 2026Article
- Etiology and clinical outcomes in patients undergoing coronary artery bypass grafting in the second decade of life.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Ischaemia-reperfusion time differences in ST-elevation myocardial infarction in very young patients: a cohort study.Open heart · 2025Article
- The Emergence of Nanotechnology in the Prognosis and Treatment of Myocardial Infarctions.Recent patents on nanotechnology · 2025Review
- Role of lymphocyte-to-monocyte ratio as a predictive marker for diabetic coronary artery disease: A cross-sectional study.World journal of methodology · 2024Article
- SPECT-MPI for Coronary Artery Disease: A Deep Learning Approach.Acta medica Philippina · 2024Article
- Breast cancer in a Hispanic patient with Werner syndrome.Journal of radiology case reports · 2023Article
- Characterization of features and outcomes of young patients (< 45 years) presenting with ST-segment elevation myocardial infarction.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023Article
- Prediabetes and all-cause mortality in young patients undergoing coronary artery angiography: a multicenter cohort study in China.Cardiovascular diabetology · 2023Article
- Investigation Driven by Network Pharmacology on Potential Components and Mechanism of DGS, a Natural Vasoprotective Combination, for the Phytotherapy of Coronary Artery Disease.Molecules (Basel, Switzerland) · 2022Article
- Clinical Features and Long-Term Outcomes in Very Young Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries.Journal of interventional cardiology · 2022Article
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Authors and funding
9 authors.
Funding
Abstract
Coronary artery disease (CAD) is a common chronic condition in the elderly. However, the earlier CAD begins, the stronger its impact on lifestyle and costs of health and social care. The present study analyzes clinical and angiographic features and the outcome of very young patients undergoing coronary angiography due to suspected CAD, including a nested case-control study of ≤40-year-old patients referred for coronary angiography. Patients were divided into two groups: cases with significant angiographic stenosis, and controls with non-significant stenosis. Of the 19,321 coronary angiographies performed in our center in a period of 10 years, 504 (2.6%) were in patients ≤40 years. The most common cardiovascular risk factors for significant CAD were smoking (OR 2.96; 95% CI 1.65-5.37), dyslipidemia (OR 2.18; 95% CI 1.27-3.82), and family history of CAD (OR 1.95; 95% CI 1.05-3.75). The incidence of major adverse cardiovascular events (MACE) at follow-up was significantly higher in the cases compared to controls (HR 2.71; 95% CI 1.44-5.11). Three conventional coronary risk factors were directly related to the early signs of CAD. MACE in the long-term follow-up is associated to dyslipidaemia and hypertriglyceridemia. Focusing efforts for the adequate control of CAD in young patients is a priority given the high socio-medical cost that this disease entails to society.
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