Evidence map›Paper›PMID 35323496›Full record

ArticleMarine drugs2022

In Vitro and In Vivo Dendritic Cell Immune Stimulation Effect of Low Molecular Weight Fucoidan from New Zealand

Litong Liu, Xu Yang, Pengfei Yuan, Shanshan Cai, Jing Bao, Yanan Zhao, Alimu Aimaier, Adila Aipire, Jun Lu, Jinyao Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Marine drugs · 2026
    Article
  3. Review
  4. Therapeutic Prospects ofMarine drugs · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Litong LiuXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Xu YangSchool of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland 1010, New Zealand.
Pengfei YuanXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Shanshan CaiXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Jing BaoXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Yanan ZhaoXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Alimu AimaierXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Adila AipireXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Jun LuSchool of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland 1010, New Zealand.ORCID 0000-0003-0225-6643
Jinyao LiXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.ORCID 0000-0002-3295-6096
Xinjiang University · CNAuckland University of Technology · NZ

Funding

Education New Zealand NZ-China Tripartite Partnership Fund AUT-13772National Natural Science Foundation of China U1803381Royal Society of New Zealand Catalyst Seeding Fund 21-AUT-005-CSG
6 · The paper itself

Abstract

Low molecular weight fucoidan (LMWF) has been reported to have immunomodulation effects through the increase of the activation and function of macrophages. In this study, the regulating effect of LMWF from

Indexed as

UndariaAnimalsCell MovementCell ProliferationDendritic CellsImmunologic FactorsInterleukin-12 Subunit p40MiceMice, Inbred C57BLMice, Inbred ICRMitogen-Activated Protein KinasesMolecular WeightNew ZealandNF-kappa BPolysaccharidesSpleenfucoidanImmunologic FactorsInterleukin-12 Subunit p40Mitogen-Activated Protein KinasesNF-kappa BPolysaccharidesTlr4 protein, mouseTnf protein, mouseToll-Like Receptor 4Tumor Necrosis Factor-alphadendritic cellsimmune stimulationlow molecular weight fucoidan (LMWF)New ZealandUndaria pinnatifida

Identifiers

PMID35323496
PMCPMC8949674
OpenAlexW4220654250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.