Evidence map›Paper›PMID 35323466›Full record

ArticleMarine drugs2022

First Identification of 12β-Deoxygonyautoxin 5 (12α-Gonyautoxinol 5) in the Cyanobacterium

Michiru Akamatsu, Ryosuke Hirozumi, Yuko Cho, Yuta Kudo, Keiichi Konoki, Yasukatsu Oshima, Mari Yotsu-Yamashita

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. The Chemistry of Phytoplankton.Chemical reviews · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michiru AkamatsuGraduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Ryosuke HirozumiGraduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Yuko ChoGraduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Yuta KudoGraduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0002-1586-2004
Keiichi KonokiGraduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0001-5788-5426
Yasukatsu OshimaGraduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan.
Mari Yotsu-YamashitaGraduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0002-5009-0409
Tohoku University · JP

Funding

Japan Society for the Promotion of Science JP19H04636, JP17H06406, JP20H02921, JP19K22266,JP 19K06232Uehara Memorial Foundation 2020
6 · The paper itself

Abstract

Saxitoxin and its analogues, paralytic shellfish toxins (PSTs), are potent and specific voltage-gated sodium channel blockers. These toxins are produced by some species of freshwater cyanobacteria and marine dinoflagellates. We previously identified several biosynthetic intermediates of PSTs, as well as new analogues, from such organisms and proposed the biosynthetic and metabolic pathways of PSTs. In this study, 12β-deoxygonyautoxin 5 (12α-gonyautoxinol 5 = gonyautoxin 5-12(

Indexed as

CyanobacteriaDinoflagellidaMolecular StructureSaxitoxingonyautoxin VSaxitoxinsaxitoxinol12β-deoxygonyautoxin 5 (12α-gonyautoxinol 5)12β-deoxysaxitoxin (12α-saxitoxinol)Alexandrium pacificumDolichospermum circinaleparalytic shellfish toxinssaxitoxin

Identifiers

PMID35323466
PMCPMC8954441
OpenAlexW4214713913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.