Evidence map›Paper›PMID 35323462›Full record

ArticleMarine drugs2022

Neoechinulin A as a Promising SARS-CoV-2 M

Hani A Alhadrami, Gaia Burgio, Bathini Thissera, Raha Orfali, Suzan E Jiffri, Mohammed Yaseen, Ahmed M Sayed, Mostafa E Rateb

Abstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Antimicrobial Compounds FromInternational journal of microbiology · 2025
    Article
  6. Consensus Pharmacophore Strategy For Identifying Novel SARS-Cov-2 MJournal of chemical information and modeling · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Journal of inflammation research · 2023
    Article
  16. A Comprehensive In Silico Study of New Metabolites fromMolecules (Basel, Switzerland) · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. A Review on Bioactive Compounds from Marine-DerivedJournal of microbiology and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hani A AlhadramiDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, P.O. Box 80402, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-4822-1895
Gaia BurgioSchool of Computing, Engineering and Physical Sciences, University of the West of Scotland, Paisley PA1 2BE, UK.
Bathini ThisseraSchool of Computing, Engineering and Physical Sciences, University of the West of Scotland, Paisley PA1 2BE, UK.ORCID 0000-0002-0998-4187
Raha OrfaliDepartment of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.
Suzan E JiffriKing Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80402, Jeddah 21589, Saudi Arabia.
Mohammed YaseenSchool of Computing, Engineering and Physical Sciences, University of the West of Scotland, Paisley PA1 2BE, UK.ORCID 0000-0002-2460-1893
Ahmed M SayedDepartment of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef 62513, Egypt.ORCID 0000-0002-1442-183X
Mostafa E RatebSchool of Computing, Engineering and Physical Sciences, University of the West of Scotland, Paisley PA1 2BE, UK.ORCID 0000-0003-4043-2687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic and its continuing emerging variants emphasize the need to discover appropriate treatment, where vaccines alone have failed to show complete protection against the new variants of the virus. Therefore, treatment of the infected cases is critical. This paper discusses the bio-guided isolation of three indole diketopiperazine alkaloids, neoechinulin A (

Indexed as

AlkaloidsAntiviral AgentsAspergillus fumigatusCoronavirus 3C ProteasesCysteine Proteinase InhibitorsIndole AlkaloidsMolecular Docking SimulationMolecular Dynamics SimulationPiperazinesSARS-CoV-2AlkaloidsAntiviral AgentsCoronavirus 3C ProteasesCysteine Proteinase InhibitorsechinulineeurocristatineIndole Alkaloidsneoechinulin APiperazinesAspergillus fumigatusmolecular dockingneoechinulin ASARS-CoV-2 Mprosteered molecular dynamics simulation

Identifiers

PMID35323462
PMCPMC8955780

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.