Evidence map›Paper›PMID 35323415›Full record

ArticleBiosensors2022

An Integrated Multiple Electrochemical miRNA Sensing System Embedded into a Microfluidic Chip.

Pedro Gonzalez-Losada, Martina Freisa, Claire Poujouly, Jean Gamby

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pedro Gonzalez-LosadaCentre de Nanosciences et de Nanotechnologies, Université Paris-Saclay, CNRS, 91120 Palaiseau, France.ORCID 0000-0003-4950-2290
Martina FreisaCentre de Nanosciences et de Nanotechnologies, Université Paris-Saclay, CNRS, 91120 Palaiseau, France.
Claire PoujoulyCentre de Nanosciences et de Nanotechnologies, Université Paris-Saclay, CNRS, 91120 Palaiseau, France.
Jean GambyCentre de Nanosciences et de Nanotechnologies, Université Paris-Saclay, CNRS, 91120 Palaiseau, France.ORCID 0000-0001-7613-8872

Funding

Agence Nationale de la Recherche ANR-10-LABX-0035French National Centre for Scientific Research PREMATURATION
6 · The paper itself

Abstract

In this article, we present the design, fabrication and characterization of a microfluidic device and a dedicated electronic system to perform 8 multiplexed electrochemical measurements of synthetic miRNA strands, as well as the biochemical protocols developed for the functionalization of the electrodes and the quantification experiments. The outcomes of this work highlight that the parallelization of eight microchannels containing 2-electrode cells driven by the dedicated electronics offers a solution as robust as a conventional 3-electrode cell and commercially available potentiostats. In addition, this solution presents the advantage of simultaneously reduce the microfabrication complexity, as well as offering an integrated; multiplexed and portable system for the quantification of miRNA. The results presented demonstrate that the system shows a linear response on concentrations down to 10

Indexed as

MicrofluidicsMicroRNAsElectrochemical TechniquesElectrodesLab-On-A-Chip DevicesMicroRNAscyclic voltammetryelectrochemical detectionmicrofabricationmicrofluidicsmicroRNAreadout electronics

Identifiers

PMID35323415
PMCPMC8946844

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.