Evidence map›Paper›PMID 35323408›Full record

ArticleBiosensors2022

Microsphere Peptide-Based Immunoassay for the Detection of Recombinant Bovine Somatotropin in Injection Preparations.

Nathalie G E Smits, Toine F H Bovee, Sidharam P Pujari, Leendert A van Ginkel, Michel W F Nielen, Bauke Albada

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nathalie G E SmitsWageningen Food Safety Research, Wageningen University and Research, 6700 AE Wageningen, The Netherlands.ORCID 0000-0001-8482-4610
Toine F H BoveeWageningen Food Safety Research, Wageningen University and Research, 6700 AE Wageningen, The Netherlands.ORCID 0000-0002-6669-0417
Sidharam P PujariLaboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands.ORCID 0000-0003-0479-8884
Leendert A van GinkelWageningen Food Safety Research, Wageningen University and Research, 6700 AE Wageningen, The Netherlands.
Michel W F NielenWageningen Food Safety Research, Wageningen University and Research, 6700 AE Wageningen, The Netherlands.ORCID 0000-0003-4634-0249
Bauke AlbadaLaboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Wageningen University & Research · NL

Funding

Dutch ministry of economic affairs 1277353901European Commission DG Health and Food Safety (EURL; Brussels, Belgium)
6 · The paper itself

Abstract

The use of peptides in immunoassays can be favored over the use of the full protein when more cost effective or less toxic approaches are needed, or when access to the full protein is lacking. Due to restricted access to recombinant bovine somatotropin (rbST), a protein enhancing growth and lactating performances of livestock, which use has been banned in the EU, Canada and Australia (amongst others), we developed a peptide-based biorecognition assay on an imaging planar array analyzer. For this, we identified the rbST epitope that is responsible for binding to the rbST-targeting monoclonal antibody 4H12 (MAb 4H12) to be

Indexed as

Growth HormoneLactationAnimalsCattleFemaleHorsesImmunoassayMicrospheresRecombinant ProteinsSwineGrowth HormoneRecombinant Proteinsbiorecognitionepitope mappingpeptide-based immunoassayrecombinant bovine somatotropinsuspension array

Identifiers

PMID35323408
PMCPMC8946150
OpenAlexW4214701574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.