Evidence map›Paper›PMID 35323374›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Genomic Landscape of Non-Small Cell Lung Cancer (NSCLC) in East Asia Using Circulating Tumor DNA (ctDNA) in Clinical Practice.

Byoung Chul Cho, Herbert H F Loong, Chun-Ming Tsai, Man Lung P Teo, Hye Ryun Kim, Sun Min Lim, Suyog Jain, Steve Olsen, Keunchil Park

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Byoung Chul ChoDivision of Medical Oncology, Yonsei Cancer Center, Seoul 03722, Korea.
Herbert H F LoongDepartment of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Chun-Ming TsaiDepartment of Oncology, Veterans General Hospital, Taipei 112, Taiwan.
Man Lung P TeoICON Cancer Centre, Hong Kong SAR, China.
Hye Ryun KimDivision of Medical Oncology, Yonsei Cancer Center, Seoul 03722, Korea.
Sun Min LimDivision of Medical Oncology, Yonsei Cancer Center, Seoul 03722, Korea.
Suyog JainDepartment of Medical Affairs, Guardant Health AMEA, Singapore 138543, Singapore.ORCID 0000-0002-2223-9181
Steve OlsenDepartment of Medical Affairs, Guardant Health AMEA, Singapore 138543, Singapore.ORCID 0000-0003-0926-2384
Keunchil ParkSungkyunkwan University School of Medicine, Seoul 2066, Korea.ORCID 0000-0002-4846-7449
Yonsei University · KRChinese University of Hong Kong · HKSungkyunkwan University · KRTaipei Veterans General Hospital · TW

Funding

Guardant Health Asia, Middle East & Africa Inc. NA
6 · The paper itself

Abstract

Plasma-based next-generation sequencing (NGS) has demonstrated the potential to guide the personalized treatment of non-small cell lung cancer (NSCLC). Inherent differences in mutational genomic profiles of NSCLC exist between Asian and Western populations. However, the published mutational genomic data of NSCLC has largely focused on Western populations. We retrospectively analyzed results from comprehensive NGS of plasma (Guardant360

Indexed as

Carcinoma, Non-Small-Cell LungCirculating Tumor DNALung NeoplasmsErbB ReceptorsHumansMutationProtein Kinase InhibitorsProto-Oncogene Proteins p21(ras)Retrospective StudiesCirculating Tumor DNAErbB ReceptorsProtein Kinase InhibitorsProto-Oncogene Proteins p21(ras)East Asiagenomic profilingliquid biopsynext-generation sequencingnon-small cell lung cancer

Identifiers

PMID35323374
PMCPMC8946965
OpenAlexW4221061124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.