ArticleCurrent oncology (Toronto, Ont.)2022
Electrochemotherapy Is Effective in the Treatment of Bone Metastases.
Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07323017 (Electrochemotherapy in Musculoskeletal Tumors), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Electrochemotherapy in Musculoskeletal Tumors: A Quantitative Assessment of Tumor Size Variations and Treatment-related Pain Reduction.
Who cites it
19 citing papers in PubMed, 23 citations in OpenAlex.
- A Phalangeal Bone Lesion Managed as a Vascular Malformation: Digit-Preserving Bleomycin Electrosclerotherapy.Cardiovascular and interventional radiology · 2026Article
- Electrochemotherapy for cutaneous tumors combined with tumor irradiation before or after treatment: feasibility, safety, and effectiveness.Radiology and oncology · 2026Article
- Locoregional Treatment of Bone Metastases in a Lung Cancer Patient: A Case Report Using Multiple Techniques: Electrochemotherapy, Cryoablation, and Cementoplasty.Reports (MDPI) · 2026Article
- The Rising Power of Electrochemotherapy in Musculoskeletal Oncology.Current oncology (Toronto, Ont.) · 2026Review
- Electrochemotherapy of spinal metastasis using transpedicular approach: a preclinical safety animal study.European radiology experimental · 2025Article
- Beyond the Scalpel: the Role of Image-Guided Thermal Ablation in Management of Metastatic Renal Cell Carcinoma in the Era of Immunotherapy.Cardiovascular and interventional radiology · 2025Review
- Electrochemotherapy in the Treatment of Bone Metastases: A Narrative Review.Cardiovascular and interventional radiology · 2025Review
- Recent Advances in Interventional Management of Extracranial Vascular Malformations in Children.Seminars in interventional radiology · 2025Review
- Tumor ablation in children.Pediatric radiology · 2025Review
- Reversible electroporation for cancer therapy.The British journal of radiology · 2025Review
- Application of a new coaxial bipolar electrode for the treatment of vertebral metastases: a pilot study in an ovine model.Frontiers in medicine · 2025Article
- Organotropic metastasis in colorectal cancer: integrating molecular pathways with therapeutic opportunities.Frontiers in immunology · 2025Review
- Inflammatory low back pain-associated malignancies mimicking spondylarthritis.Clinical rheumatology · 2024Article
- Threshold Interphase Delay for Bipolar Pulses to Prevent Cancellation Phenomenon during Electrochemotherapy.International journal of molecular sciences · 2024Article
- Electrochemotherapy in Aggressive Hemangioma of the Spine: A Case Series and Narrative Literature Review.Journal of clinical medicine · 2024Article
- Electrochemotherapy in the Treatment of Bone Metastases: A Systematic Review.Journal of clinical medicine · 2023Review
- Optimal Dosing and Patient Selection for Electrochemotherapy in Solid Abdominal Organ and Bone Tumors.Bioengineering (Basel, Switzerland) · 2023Review
- Review
- Treatment of Bone Metastasis.Current oncology (Toronto, Ont.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone metastases induce pain, risk of fracture, and neural compression, and reduced mobility and quality of life. Electrochemotherapy (ECT) is a minimally invasive local treatment based on a high-voltage electric pulse combined with an anticancer drug. Preclinical and clinical studies have supported the use of ECT in patients with metastatic bone disease, demonstrating that it does not damage the mineral structure of the bone and its regenerative capacity, and that is feasible and efficient for the treatment of bone metastases. Since 2009, 88 patients with bone metastasis have received ECT at the Rizzoli Institute. 2014 saw the start of a registry of patients with bone metastases treated with ECT, whose data are recorded in a shared database. We share the Rizzoli Institute experience of 38 patients treated with ECT for a bone metastasis, excluding patients not included in the registry (before 2014) and those treated with bone fixation. Mean follow-up was 2 months (1-52). Response to treatment using RECIST criteria was 29% objective responses, 59% stable disease, and 16% progressive disease. Using PERCIST, the response was 36% OR, 14% SD, and 50% PD with no significant differences between the two criteria. A significant decrease in pain and better quality of life was observed at FU.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.